Regulation of the orphan nuclear receptor Nr2f2 by the DFNA15 deafness gene Pou4f3.
Hair cells are the mechanotransducing cells of the inner ear that are essential for hearing and balance. POU4F3--a POU-domain transcription factor selectively expressed by these cells--has been shown to be essential for hair cell differentiation and survival in mice and its mutation in humans underl...
Main Authors: | Chrysostomos Tornari, Emily R Towers, Jonathan E Gale, Sally J Dawson |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2014-01-01
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Series: | PLoS ONE |
Online Access: | http://europepmc.org/articles/PMC4221282?pdf=render |
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