Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors

The laterodorsal tegmental nucleus (LDT) is known to influence reward processing through its projections to the VTA. Here, the authors report that the cholinergic projections from the LDT to the nucleus accumbens play an important role in motivation and positive reinforcement behaviors.

Bibliographic Details
Main Authors:	Bárbara Coimbra, Carina Soares-Cunha, Nivaldo A P Vasconcelos, Ana Verónica Domingues, Sónia Borges, Nuno Sousa, Ana João Rodrigues
Format:	Article
Language:	English
Published:	Nature Publishing Group 2019-09-01
Series:	Nature Communications
Online Access:	https://doi.org/10.1038/s41467-019-11557-3

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spelling	doaj-f56df6bde61a4e5f9efc8b868a43fe572021-05-11T12:28:39ZengNature Publishing GroupNature Communications2041-17232019-09-0110111510.1038/s41467-019-11557-3Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviorsBárbara Coimbra0Carina Soares-Cunha1Nivaldo A P Vasconcelos2Ana Verónica Domingues3Sónia Borges4Nuno Sousa5Ana João Rodrigues6Life and Health Sciences Research Institute (ICVS), School of Medicine, University of MinhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of MinhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of MinhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of MinhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of MinhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of MinhoLife and Health Sciences Research Institute (ICVS), School of Medicine, University of MinhoThe laterodorsal tegmental nucleus (LDT) is known to influence reward processing through its projections to the VTA. Here, the authors report that the cholinergic projections from the LDT to the nucleus accumbens play an important role in motivation and positive reinforcement behaviors.https://doi.org/10.1038/s41467-019-11557-3
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Bárbara Coimbra Carina Soares-Cunha Nivaldo A P Vasconcelos Ana Verónica Domingues Sónia Borges Nuno Sousa Ana João Rodrigues
spellingShingle	Bárbara Coimbra Carina Soares-Cunha Nivaldo A P Vasconcelos Ana Verónica Domingues Sónia Borges Nuno Sousa Ana João Rodrigues Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors Nature Communications
author_facet	Bárbara Coimbra Carina Soares-Cunha Nivaldo A P Vasconcelos Ana Verónica Domingues Sónia Borges Nuno Sousa Ana João Rodrigues
author_sort	Bárbara Coimbra
title	Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_short	Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_full	Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_fullStr	Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_full_unstemmed	Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
title_sort	role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors
publisher	Nature Publishing Group
series	Nature Communications
issn	2041-1723
publishDate	2019-09-01
description	The laterodorsal tegmental nucleus (LDT) is known to influence reward processing through its projections to the VTA. Here, the authors report that the cholinergic projections from the LDT to the nucleus accumbens play an important role in motivation and positive reinforcement behaviors.
url	https://doi.org/10.1038/s41467-019-11557-3
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Role of laterodorsal tegmentum projections to nucleus accumbens in reward-related behaviors

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