Comparison of desensitizing efficacy of an Iranian dentifrice and a commercially available dentifrice: a randomized double-blinded controlled clinical trial.

• Main Authors: Neda Moslemi, Maryam Johari, Mohammad Sadegh Ahmad Akhoundi, Hadi Zare, Ahmad-Reza Shamshiri, Azam Khorshidian
• Format: Article
• Language: English
• Published: Tehran University of Medical Sciences 2013-07-01
• Series: Frontiers in Dentistry
• Subjects: Clinical Trial; Dentin Hypersensitivity; Potassium Nitrate; Toothpaste
• Online Access: https://jdt.tums.ac.ir/index.php/jdt/article/view/632

The aim of this randomized controlled clinical trial was to investigate the effect of a new Iranian toothpaste and a commercially available toothpaste containing desensitizing agent (5% potassium nitrate) on dentine hypersensitivity in a 24-week study.Fifty healthy volunteers, who had at least two sensitive root surfaces, completed the study period. The participants were randomly given one of the two toothpastes; Iranian (antihypersensitive Pooneh) or commercially available (fresh mint Sensodyne) toothpaste. Visual analogue scales (VASs) indicating the intensity of tooth hypersensitivity responding to tactile, airblast and cold-water stimuli were examined at baseline and weeks 2, 4, 12 and 24.Overall, VAS scores for tactile, airblast, and cold-water tests significantly reduced compared with the baseline in both groups (all P values