CAF-1 Subunits Levels Suggest Combined Treatments with PARP-Inhibitors and Ionizing Radiation in Advanced HNSCC

CAF-1 Subunits Levels Suggest Combined Treatments with PARP-Inhibitors and Ionizing Radiation in Advanced HNSCC

Oral (OSCC) and oropharyngeal (OPSCC) squamous cell carcinomas show high morbidity and mortality rates. We aimed to investigate the role of the “Chromatin Assembly Factor-1” (CAF-1) p60 and p150 subunits, involved in DNA repair and replication, in OSCC and OPSCC progression and i...

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Bibliographic Details
Main Authors:	Francesco Morra, Francesco Merolla, Ida Picardi, Daniela Russo, Gennaro Ilardi, Silvia Varricchio, Federica Liotti, Roberto Pacelli, Luca Palazzo, Massimo Mascolo, Angela Celetti, Stefania Staibano
Format:	Article
Language:	English
Published:	MDPI AG 2019-10-01
Series:	Cancers
Subjects:	head and neck squamous cell carcinoma cal27 scc90 p60/p150 caf-1 subunits dna repair homologous recombination biomarkers personalized treatment
Online Access:	https://www.mdpi.com/2072-6694/11/10/1582

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