Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?

Abstract CSF (Cerebrospinal Fluid) xanthochromia by spectroscopy should not be dismissed in the context of hyperbilirubinemia in a patient with sickle cell anemia. Xanthochromia detected by spectrophotometry offers a vital clue that further invasive diagnosis is required.

Bibliographic Details
Main Authors: Wan Yung Siu, William Thomas, Rikin Trivedi, Alexandra Hogan, Umbareen Siddiqi, Anita Sarker, Martin Wolfgang Besser
Format: Article
Language:English
Published: Wiley 2020-05-01
Series:Clinical Case Reports
Subjects:
Online Access:https://doi.org/10.1002/ccr3.2775
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spelling doaj-f58928588b964b989184c1ff33c6b0842020-11-25T02:13:43ZengWileyClinical Case Reports2050-09042020-05-018589489910.1002/ccr3.2775Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?Wan Yung Siu0William Thomas1Rikin Trivedi2Alexandra Hogan3Umbareen Siddiqi4Anita Sarker5Martin Wolfgang Besser6Department of Haematology Addenbrooke's Hospital Cambridge UKDepartment of Haematology Addenbrooke's Hospital Cambridge UKDepartment of Neurosurgery Addenbrooke's Hospital Cambridge UKDepartment of Anaesthetics Addenbrooke's Hospital Cambridge UKDepartment of Anaesthetics Addenbrooke's Hospital Cambridge UKDepartment of Biochemistry Addenbrooke's Hospital Cambridge UKDepartment of Haematology Addenbrooke's Hospital Cambridge UKAbstract CSF (Cerebrospinal Fluid) xanthochromia by spectroscopy should not be dismissed in the context of hyperbilirubinemia in a patient with sickle cell anemia. Xanthochromia detected by spectrophotometry offers a vital clue that further invasive diagnosis is required.https://doi.org/10.1002/ccr3.2775CSF xanthochromiapolycystic kidney diseaseSickle cell anemiaspectroscopysubarachnoid hemorrhage
collection DOAJ
language English
format Article
sources DOAJ
author Wan Yung Siu
William Thomas
Rikin Trivedi
Alexandra Hogan
Umbareen Siddiqi
Anita Sarker
Martin Wolfgang Besser
spellingShingle Wan Yung Siu
William Thomas
Rikin Trivedi
Alexandra Hogan
Umbareen Siddiqi
Anita Sarker
Martin Wolfgang Besser
Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?
Clinical Case Reports
CSF xanthochromia
polycystic kidney disease
Sickle cell anemia
spectroscopy
subarachnoid hemorrhage
author_facet Wan Yung Siu
William Thomas
Rikin Trivedi
Alexandra Hogan
Umbareen Siddiqi
Anita Sarker
Martin Wolfgang Besser
author_sort Wan Yung Siu
title Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?
title_short Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?
title_full Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?
title_fullStr Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?
title_full_unstemmed Can CSF spectrophotometry for “Xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative MRI or CT angiogram despite hyperbilirubinemia?
title_sort can csf spectrophotometry for “xanthochromia” be used to detect leaking subarachnoid aneurysms in patients with sickle cell anemia with negative mri or ct angiogram despite hyperbilirubinemia?
publisher Wiley
series Clinical Case Reports
issn 2050-0904
publishDate 2020-05-01
description Abstract CSF (Cerebrospinal Fluid) xanthochromia by spectroscopy should not be dismissed in the context of hyperbilirubinemia in a patient with sickle cell anemia. Xanthochromia detected by spectrophotometry offers a vital clue that further invasive diagnosis is required.
topic CSF xanthochromia
polycystic kidney disease
Sickle cell anemia
spectroscopy
subarachnoid hemorrhage
url https://doi.org/10.1002/ccr3.2775
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