Induction of fatty liver by Coleus forskohlii extract through enhancement of de novo triglyceride synthesis in mice

Induction of fatty liver by Coleus forskohlii extract through enhancement of de novo triglyceride synthesis in mice

Coleus forskohlii extract (CFE), an herbal ingredient, is used for weight-loss products. CFE's alleged efficacy is attributed to forskolin. However, CFE has been shown to induce fatty liver in mice, with components other than forskolin playing a part in this effect. The present study addressed...

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Bibliographic Details
Main Authors: Keizo Umegaki, Yuko Yamazaki, Kaori Yokotani, Tsuyoshi Chiba, Yoko Sato, Fumio Shimura
Format: Article
Language:English
Published: Elsevier 2014-01-01
Series:Toxicology Reports
Subjects:
Coleus forskohlii
Forskolin
Fatty liver
De novo synthesis
PPARγ
Fsp27
Dietary supplement
Online Access:http://www.sciencedirect.com/science/article/pii/S2214750014000948

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