K-RAS and P53 Mutations in Association with COX-2 and Htert Expression and Clinico-Pathological Status of Nsclc Patients
We evaluated the occurrence of mutations in P53, K-RAS, COX-2, expression of COX-2 and hTERT and relations among clinicopathological signs. P53 mutations were identified in 34.4% of tumours, the majority of them occurring in SCC (squamous cell carcinoma, 55.6%). K-RAS was mutated in 12.2% of NSCLC t...
| Main Authors: | , , |
|---|---|
| Format: | Article |
| Language: | English |
| Published: |
Hindawi Limited
2008-01-01
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| Series: | Disease Markers |
| Online Access: | http://dx.doi.org/10.1155/2008/232743 |