A review on extraction techniques and therapeutic value of polar bioactives from Asian medicinal herbs: Case study on Orthosiphon aristatus, Eurycoma longifolia and Andrographis paniculata

• Main Authors: Nur Amanina Abd Aziz, Rosnani Hasham, Mohamad Roji Sarmidi, Siti Hasyimah Suhaimi, Mohamad Khairul Hafiz Idris
• Format: Article
• Language: English
• Published: Elsevier 2021-02-01
• Series: Saudi Pharmaceutical Journal
• Subjects: Medicinal plants; Orthosiphon aristatus (OA); Eurycoma longifolia (EL); Andrographis paniculata (AP); Extraction methods; Rosmarinic acid
• Online Access: http://www.sciencedirect.com/science/article/pii/S1319016421000025

Medicinal plants have gained much interest in the prevention and treatment of common human disease such as cold and fever, hypertension and postpartum. Bioactive compounds from medicinal plants were synthesised using effective extraction methods which have important roles in the pharmaceutical product development. Orthosiphon aristatus (OA), Eurycoma longifolia (EL) and Andrographis paniculata (AP) are among popular medicinal herbs in Southeast Asia. The major compounds for these medicinal plants are polar bioactive compounds (rosmarinic acid, eurycomanone and andrographolide) which have multiple benefits to human health. The bioactive compounds are used as a drug to function against a variety of diseases with the support of scientific evidence. This paper was intended to prepare a complete review about the extraction techniques (e.g. OA, EL and AP) of these medicinal plants based on existing studies and scientific works. Suitable solvents and techniques to obtain their major bioactive compounds and their therapeutic potentials were discussed.