A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).

A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).

The Semi-solid Control Diagram (SSCD) is a new tool designed for the study of different excipients and different semi-solid dosage forms. It can be used to review and evaluate different formulations and/or batches and facilitate the selection of one of them that will present the most suitable galeni...

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Main Authors: Anna Nardi-Ricart, Maria Jose Linares, Faviola Villca-Pozo, Pilar Pérez-Lozano, Josep Maria Suñé-Negre, Lara Bachs-deMiquel, Manel Roig-Carreras, Marc Suñé-Pou, Isaac Nofrerias-Roig, Encarna García-Montoya
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6128454?pdf=render
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spelling doaj-f5b2436a282c4df5b00d8aeb93c848f32020-11-24T21:56:45ZengPublic Library of Science (PLoS)PLoS ONE1932-62032018-01-01139e020164310.1371/journal.pone.0201643A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).Anna Nardi-RicartMaria Jose LinaresFaviola Villca-PozoPilar Pérez-LozanoJosep Maria Suñé-NegreLara Bachs-deMiquelManel Roig-CarrerasMarc Suñé-PouIsaac Nofrerias-RoigEncarna García-MontoyaThe Semi-solid Control Diagram (SSCD) is a new tool designed for the study of different excipients and different semi-solid dosage forms. It can be used to review and evaluate different formulations and/or batches and facilitate the selection of one of them that will present the most suitable galenic characteristics for topical application. It is also useful to track stability studies by comparing the diagrams, which allows to measure the impact of subjecting the formulation to different conditions and times to be examined. In this study, the Semi-solid Control Diagram (SSCD) is used as an instrument for studying and evaluating semi-solid pharmaceutical dosage forms, by comparing several different semisolid preparations (lipogels). With these results, the tool is validated and the best formulation has been discriminated from the others.http://europepmc.org/articles/PMC6128454?pdf=render
collection DOAJ
language English
format Article
sources DOAJ
author Anna Nardi-Ricart
Maria Jose Linares
Faviola Villca-Pozo
Pilar Pérez-Lozano
Josep Maria Suñé-Negre
Lara Bachs-deMiquel
Manel Roig-Carreras
Marc Suñé-Pou
Isaac Nofrerias-Roig
Encarna García-Montoya
spellingShingle Anna Nardi-Ricart
Maria Jose Linares
Faviola Villca-Pozo
Pilar Pérez-Lozano
Josep Maria Suñé-Negre
Lara Bachs-deMiquel
Manel Roig-Carreras
Marc Suñé-Pou
Isaac Nofrerias-Roig
Encarna García-Montoya
A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).
PLoS ONE
author_facet Anna Nardi-Ricart
Maria Jose Linares
Faviola Villca-Pozo
Pilar Pérez-Lozano
Josep Maria Suñé-Negre
Lara Bachs-deMiquel
Manel Roig-Carreras
Marc Suñé-Pou
Isaac Nofrerias-Roig
Encarna García-Montoya
author_sort Anna Nardi-Ricart
title A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).
title_short A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).
title_full A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).
title_fullStr A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).
title_full_unstemmed A new design for the review and appraisal of semi-solid dosage forms: Semi-solid Control Diagram (SSCD).
title_sort new design for the review and appraisal of semi-solid dosage forms: semi-solid control diagram (sscd).
publisher Public Library of Science (PLoS)
series PLoS ONE
issn 1932-6203
publishDate 2018-01-01
description The Semi-solid Control Diagram (SSCD) is a new tool designed for the study of different excipients and different semi-solid dosage forms. It can be used to review and evaluate different formulations and/or batches and facilitate the selection of one of them that will present the most suitable galenic characteristics for topical application. It is also useful to track stability studies by comparing the diagrams, which allows to measure the impact of subjecting the formulation to different conditions and times to be examined. In this study, the Semi-solid Control Diagram (SSCD) is used as an instrument for studying and evaluating semi-solid pharmaceutical dosage forms, by comparing several different semisolid preparations (lipogels). With these results, the tool is validated and the best formulation has been discriminated from the others.
url http://europepmc.org/articles/PMC6128454?pdf=render
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