Preclinical evaluation of a MAGE-A3 vaccination utilizing the oncolytic Maraba virus currently in first-in-human trials
Multiple immunotherapeutics have been approved for cancer patients, however advanced solid tumors are frequently refractory to treatment. We evaluated the safety and immunogenicity of a vaccination approach with multimodal oncolytic potential in non-human primates (NHP) (Macaca fascicularis). Primat...
Main Authors: | Jonathan G. Pol, Sergio A. Acuna, Beta Yadollahi, Nan Tang, Kyle B. Stephenson, Matthew J. Atherton, David Hanwell, Alexander El-Warrak, Alyssa Goldstein, Badru Moloo, Patricia V. Turner, Roberto Lopez, Sandra LaFrance, Carole Evelegh, Galina Denisova, Robin Parsons, Jamie Millar, Gautier Stoll, Chantal G. Martin, Julia Pomoransky, Caroline J. Breitbach, Jonathan L. Bramson, John C. Bell, Yonghong Wan, David F. Stojdl, Brian D. Lichty, J. Andrea McCart |
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Format: | Article |
Language: | English |
Published: |
Taylor & Francis Group
2019-01-01
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Series: | OncoImmunology |
Subjects: | |
Online Access: | http://dx.doi.org/10.1080/2162402X.2018.1512329 |
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