Epidemic models with heterogeneous mixing and indirect transmission

We develop an age of infection model with heterogeneous mixing in which indirect pathogen transmission is considered as a good way to describe contact that is usually considered as direct and we also incorporate virus shedding as a function of age of infection. The simplest form of SIRP epidemic mod...

Full description

Bibliographic Details
Main Author: Jummy Funke David
Format: Article
Language:English
Published: Taylor & Francis Group 2018-01-01
Series:Journal of Biological Dynamics
Subjects:
Online Access:http://dx.doi.org/10.1080/17513758.2018.1467506
Description
Summary:We develop an age of infection model with heterogeneous mixing in which indirect pathogen transmission is considered as a good way to describe contact that is usually considered as direct and we also incorporate virus shedding as a function of age of infection. The simplest form of SIRP epidemic model is introduced and it serves as a basis for the age of infection model and a 2-patch SIRP model where the risk of infection is solely dependent on the residence times and other environmental factors. The computation of the basic reproduction number $ \mathcal {R}_0 $ , the initial exponential growth rate and the final size relation is done and by mathematical analysis, we study the impact of patches connection and use the final size relation to analyse the ability of disease to invade over a short period of time.
ISSN:1751-3758
1751-3766