RNAi Screen Identifies Novel Regulators of RNP Granules in the Caenorhabditis elegans Germ Line

RNAi Screen Identifies Novel Regulators of RNP Granules in the Caenorhabditis elegans Germ Line

Complexes of RNA and RNA binding proteins form large-scale supramolecular structures under many cellular contexts. In Caenorhabditis elegans, small germ granules are present in the germ line that share characteristics with liquid droplets that undergo phase transitions. In meiotically-arrested oocyt...

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Bibliographic Details
Main Authors: Megan P. Wood, Angela Hollis, Ashley L. Severance, Megan L. Karrick, Jennifer A. Schisa
Format: Article
Language:English
Published: Oxford University Press 2016-08-01
Series:G3: Genes, Genomes, Genetics
Subjects:
RNP granule
oocyte quality
C. elegans
aging
germ line
Online Access:http://g3journal.org/lookup/doi/10.1534/g3.116.031559

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