Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy

The purpose of this work is to improve the cytocompatibility and corrosion resistance of magnesium alloy in the hope of preparing a biodegradable medical material. The aminated hydroxyethyl cellulose-induced biomimetic hydroxyapatite coating was successfully prepared on AZ31 magnesium alloy surface...

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Main Authors:	Bowu Zhu, Yimeng Xu, Jing Sun, Lei Yang, Changgang Guo, Jun Liang, Baocheng Cao
Format:	Article
Language:	English
Published:	MDPI AG 2017-06-01
Series:	Metals
Subjects:	biomaterials corrosion coatings aminated hydroxyethyl cellulose magnesium alloy hydroxyapatite cytotoxicity
Online Access:	http://www.mdpi.com/2075-4701/7/6/214

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spelling	doaj-f6002a8c74bc4c5d8c630fb18ffdb4a12020-11-24T22:23:47ZengMDPI AGMetals2075-47012017-06-017621410.3390/met7060214met7060214Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium AlloyBowu Zhu0Yimeng Xu1Jing Sun2Lei Yang3Changgang Guo4Jun Liang5Baocheng Cao6School of Stomatology, Lanzhou University, Lanzhou 730000, ChinaSchool of Stomatology, Lanzhou University, Lanzhou 730000, ChinaSchool of Stomatology, Lanzhou University, Lanzhou 730000, ChinaSchool of Stomatology, Lanzhou University, Lanzhou 730000, ChinaSchool of Stomatology, Lanzhou University, Lanzhou 730000, ChinaState Key Laboratory of Solid Lubrication, Lanzhou Institute of Chemical Physics, Chinese Academy of Sciences, Lanzhou 730000, ChinaSchool of Stomatology, Lanzhou University, Lanzhou 730000, ChinaThe purpose of this work is to improve the cytocompatibility and corrosion resistance of magnesium alloy in the hope of preparing a biodegradable medical material. The aminated hydroxyethyl cellulose-induced biomimetic hydroxyapatite coating was successfully prepared on AZ31 magnesium alloy surface with a sol-gel spin coating method and biomimetic mineralization. Potentiodynamic polarization tests and electrochemical impedance spectroscopy showed that the hydroxyapatite/aminated hydroxyethyl cellulose (HA/AHEC) coating can greatly improve the corrosion resistance of AZ31 magnesium alloy and reduce the degradation speed in simulated body fluid (SBF). The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide] method and cell morphology observation results showed that the HA/AHEC coating on AZ31 magnesium alloy has excellent cytocompatibility and biological activity.http://www.mdpi.com/2075-4701/7/6/214biomaterialscorrosioncoatingsaminated hydroxyethyl cellulosemagnesium alloyhydroxyapatitecytotoxicity
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Bowu Zhu Yimeng Xu Jing Sun Lei Yang Changgang Guo Jun Liang Baocheng Cao
spellingShingle	Bowu Zhu Yimeng Xu Jing Sun Lei Yang Changgang Guo Jun Liang Baocheng Cao Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy Metals biomaterials corrosion coatings aminated hydroxyethyl cellulose magnesium alloy hydroxyapatite cytotoxicity
author_facet	Bowu Zhu Yimeng Xu Jing Sun Lei Yang Changgang Guo Jun Liang Baocheng Cao
author_sort	Bowu Zhu
title	Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy
title_short	Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy
title_full	Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy
title_fullStr	Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy
title_full_unstemmed	Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy
title_sort	preparation and characterization of aminated hydroxyethyl cellulose-induced biomimetic hydroxyapatite coatings on the az31 magnesium alloy
publisher	MDPI AG
series	Metals
issn	2075-4701
publishDate	2017-06-01
description	The purpose of this work is to improve the cytocompatibility and corrosion resistance of magnesium alloy in the hope of preparing a biodegradable medical material. The aminated hydroxyethyl cellulose-induced biomimetic hydroxyapatite coating was successfully prepared on AZ31 magnesium alloy surface with a sol-gel spin coating method and biomimetic mineralization. Potentiodynamic polarization tests and electrochemical impedance spectroscopy showed that the hydroxyapatite/aminated hydroxyethyl cellulose (HA/AHEC) coating can greatly improve the corrosion resistance of AZ31 magnesium alloy and reduce the degradation speed in simulated body fluid (SBF). The MTT [3-(4,5-dimethylthiazol-2-yl)-2,5-Diphenyltetrazolium bromide] method and cell morphology observation results showed that the HA/AHEC coating on AZ31 magnesium alloy has excellent cytocompatibility and biological activity.
topic	biomaterials corrosion coatings aminated hydroxyethyl cellulose magnesium alloy hydroxyapatite cytotoxicity
url	http://www.mdpi.com/2075-4701/7/6/214
work_keys_str_mv	AT bowuzhu preparationandcharacterizationofaminatedhydroxyethylcelluloseinducedbiomimetichydroxyapatitecoatingsontheaz31magnesiumalloy AT yimengxu preparationandcharacterizationofaminatedhydroxyethylcelluloseinducedbiomimetichydroxyapatitecoatingsontheaz31magnesiumalloy AT jingsun preparationandcharacterizationofaminatedhydroxyethylcelluloseinducedbiomimetichydroxyapatitecoatingsontheaz31magnesiumalloy AT leiyang preparationandcharacterizationofaminatedhydroxyethylcelluloseinducedbiomimetichydroxyapatitecoatingsontheaz31magnesiumalloy AT changgangguo preparationandcharacterizationofaminatedhydroxyethylcelluloseinducedbiomimetichydroxyapatitecoatingsontheaz31magnesiumalloy AT junliang preparationandcharacterizationofaminatedhydroxyethylcelluloseinducedbiomimetichydroxyapatitecoatingsontheaz31magnesiumalloy AT baochengcao preparationandcharacterizationofaminatedhydroxyethylcelluloseinducedbiomimetichydroxyapatitecoatingsontheaz31magnesiumalloy
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Preparation and Characterization of Aminated Hydroxyethyl Cellulose-Induced Biomimetic Hydroxyapatite Coatings on the AZ31 Magnesium Alloy

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