Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer

Understanding the Mechanisms by Which Epigenetic Modifiers Avert Therapy Resistance in Cancer

The development of resistance to anti-cancer therapeutics remains one of the core issues preventing the improvement of survival rates in cancer. Therapy resistance can arise in a multitude of ways, including the accumulation of epigenetic alterations in cancer cells. By remodeling DNA methylation pa...

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Bibliographic Details
Main Authors: Anthony Quagliano, Anilkumar Gopalakrishnapillai, Sonali P. Barwe
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-06-01
Series:Frontiers in Oncology
Subjects:
epigenetic aberrations
chemoresistance
mechanism
cancer
epigenetic drugs
epigenetic combination therapies
Online Access:https://www.frontiersin.org/article/10.3389/fonc.2020.00992/full

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