Toxoplasma gondii Type-I ROP18 Targeting Human E3 Ligase TRIM21 for Immune Escape

Toxoplasma gondii Type-I ROP18 Targeting Human E3 Ligase TRIM21 for Immune Escape

Toxoplasma gondii is an intracellular pathogen that exerts its virulence through inhibiting host’s innate immune responses, which is mainly related to the type II interferon (IFN-γ) response. IFN-γ inducible tripartite motif 21 (TRIM21), an E3 ligase, plays an important role in anti-infection respon...

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Bibliographic Details
Main Authors: Lijie Yao, Liqing Xu, Lijuan Zhou, Shuizhen Wu, Weihao Zou, Min Chen, Jiating Chen, Hongjuan Peng
Format: Article
Language:English
Published: Frontiers Media S.A. 2021-05-01
Series:Frontiers in Cell and Developmental Biology
Subjects:
Toxoplasma gondii
TRIM21
TgROP18I
NF-κB
ubiquitin
Online Access:https://www.frontiersin.org/articles/10.3389/fcell.2021.685913/full

Internet

https://www.frontiersin.org/articles/10.3389/fcell.2021.685913/full

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