Studies on synthesis of pyrimidine derivatives and their antimicrobial activity

Studies on synthesis of pyrimidine derivatives and their antimicrobial activity

A series of novel 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine derivatives were synthesized by the reaction of 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine with various sulfonyl chlorides, and their in vitro antimicrobial activity was evaluated. The synthesi...

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Main Authors: C. Mallikarjunaswamy, L. Mallesha, D.G. Bhadregowda, Othbert Pinto
Format: Article
Language:English
Published: Elsevier 2017-02-01
Series:Arabian Journal of Chemistry
Subjects:
Pyrimidine derivatives
Sulfonyl chlorides
Antimicrobial activity
Online Access:http://www.sciencedirect.com/science/article/pii/S1878535212002377
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spelling doaj-f6103891a8fb478f95c49c3e2b296c902020-11-24T22:02:06ZengElsevierArabian Journal of Chemistry1878-53522017-02-0110S1S484S49010.1016/j.arabjc.2012.10.008Studies on synthesis of pyrimidine derivatives and their antimicrobial activityC. Mallikarjunaswamy0L. Mallesha1D.G. Bhadregowda2Othbert Pinto3PG Department of Studies in Chemistry, St. Philomena's College, Bannimantap, Mysore 15, IndiaPG Department of Studies in Chemistry, JSS College of Arts, Commerce and Science, Ooty Road, Mysore 25, IndiaDepartment of Chemistry, Yuvaraja's College, University of Mysore, Mysore 5, IndiaPG Department of Studies in Chemistry, St. Philomena's College, Bannimantap, Mysore 15, IndiaA series of novel 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine derivatives were synthesized by the reaction of 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine with various sulfonyl chlorides, and their in vitro antimicrobial activity was evaluated. The synthesized compounds were characterized by elemental analyses, FT-IR, 1H NMR and LC–MS spectral studies.http://www.sciencedirect.com/science/article/pii/S1878535212002377Pyrimidine derivativesSulfonyl chloridesAntimicrobial activity
collection DOAJ
language English
format Article
sources DOAJ
author C. Mallikarjunaswamy
L. Mallesha
D.G. Bhadregowda
Othbert Pinto
spellingShingle C. Mallikarjunaswamy
L. Mallesha
D.G. Bhadregowda
Othbert Pinto
Studies on synthesis of pyrimidine derivatives and their antimicrobial activity
Arabian Journal of Chemistry
Pyrimidine derivatives
Sulfonyl chlorides
Antimicrobial activity
author_facet C. Mallikarjunaswamy
L. Mallesha
D.G. Bhadregowda
Othbert Pinto
author_sort C. Mallikarjunaswamy
title Studies on synthesis of pyrimidine derivatives and their antimicrobial activity
title_short Studies on synthesis of pyrimidine derivatives and their antimicrobial activity
title_full Studies on synthesis of pyrimidine derivatives and their antimicrobial activity
title_fullStr Studies on synthesis of pyrimidine derivatives and their antimicrobial activity
title_full_unstemmed Studies on synthesis of pyrimidine derivatives and their antimicrobial activity
title_sort studies on synthesis of pyrimidine derivatives and their antimicrobial activity
publisher Elsevier
series Arabian Journal of Chemistry
issn 1878-5352
publishDate 2017-02-01
description A series of novel 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine derivatives were synthesized by the reaction of 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine with various sulfonyl chlorides, and their in vitro antimicrobial activity was evaluated. The synthesized compounds were characterized by elemental analyses, FT-IR, 1H NMR and LC–MS spectral studies.
topic Pyrimidine derivatives
Sulfonyl chlorides
Antimicrobial activity
url http://www.sciencedirect.com/science/article/pii/S1878535212002377
work_keys_str_mv AT cmallikarjunaswamy studiesonsynthesisofpyrimidinederivativesandtheirantimicrobialactivity
AT lmallesha studiesonsynthesisofpyrimidinederivativesandtheirantimicrobialactivity
AT dgbhadregowda studiesonsynthesisofpyrimidinederivativesandtheirantimicrobialactivity
AT othbertpinto studiesonsynthesisofpyrimidinederivativesandtheirantimicrobialactivity
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