Studies on synthesis of pyrimidine derivatives and their antimicrobial activity
A series of novel 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine derivatives were synthesized by the reaction of 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine with various sulfonyl chlorides, and their in vitro antimicrobial activity was evaluated. The synthesi...
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doaj-f6103891a8fb478f95c49c3e2b296c902020-11-24T22:02:06ZengElsevierArabian Journal of Chemistry1878-53522017-02-0110S1S484S49010.1016/j.arabjc.2012.10.008Studies on synthesis of pyrimidine derivatives and their antimicrobial activityC. Mallikarjunaswamy0L. Mallesha1D.G. Bhadregowda2Othbert Pinto3PG Department of Studies in Chemistry, St. Philomena's College, Bannimantap, Mysore 15, IndiaPG Department of Studies in Chemistry, JSS College of Arts, Commerce and Science, Ooty Road, Mysore 25, IndiaDepartment of Chemistry, Yuvaraja's College, University of Mysore, Mysore 5, IndiaPG Department of Studies in Chemistry, St. Philomena's College, Bannimantap, Mysore 15, IndiaA series of novel 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine derivatives were synthesized by the reaction of 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine with various sulfonyl chlorides, and their in vitro antimicrobial activity was evaluated. The synthesized compounds were characterized by elemental analyses, FT-IR, 1H NMR and LC–MS spectral studies.http://www.sciencedirect.com/science/article/pii/S1878535212002377Pyrimidine derivativesSulfonyl chloridesAntimicrobial activity |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
C. Mallikarjunaswamy L. Mallesha D.G. Bhadregowda Othbert Pinto |
spellingShingle |
C. Mallikarjunaswamy L. Mallesha D.G. Bhadregowda Othbert Pinto Studies on synthesis of pyrimidine derivatives and their antimicrobial activity Arabian Journal of Chemistry Pyrimidine derivatives Sulfonyl chlorides Antimicrobial activity |
author_facet |
C. Mallikarjunaswamy L. Mallesha D.G. Bhadregowda Othbert Pinto |
author_sort |
C. Mallikarjunaswamy |
title |
Studies on synthesis of pyrimidine derivatives and their antimicrobial activity |
title_short |
Studies on synthesis of pyrimidine derivatives and their antimicrobial activity |
title_full |
Studies on synthesis of pyrimidine derivatives and their antimicrobial activity |
title_fullStr |
Studies on synthesis of pyrimidine derivatives and their antimicrobial activity |
title_full_unstemmed |
Studies on synthesis of pyrimidine derivatives and their antimicrobial activity |
title_sort |
studies on synthesis of pyrimidine derivatives and their antimicrobial activity |
publisher |
Elsevier |
series |
Arabian Journal of Chemistry |
issn |
1878-5352 |
publishDate |
2017-02-01 |
description |
A series of novel 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine derivatives were synthesized by the reaction of 2-(5-bromo-2-chloro-pyrimidin-4-ylsulfanyl)-4-methoxy-phenylamine with various sulfonyl chlorides, and their in vitro antimicrobial activity was evaluated. The synthesized compounds were characterized by elemental analyses, FT-IR, 1H NMR and LC–MS spectral studies. |
topic |
Pyrimidine derivatives Sulfonyl chlorides Antimicrobial activity |
url |
http://www.sciencedirect.com/science/article/pii/S1878535212002377 |
work_keys_str_mv |
AT cmallikarjunaswamy studiesonsynthesisofpyrimidinederivativesandtheirantimicrobialactivity AT lmallesha studiesonsynthesisofpyrimidinederivativesandtheirantimicrobialactivity AT dgbhadregowda studiesonsynthesisofpyrimidinederivativesandtheirantimicrobialactivity AT othbertpinto studiesonsynthesisofpyrimidinederivativesandtheirantimicrobialactivity |
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