A Wor1-Like Transcription Factor Is Essential for Virulence of Cryptococcus neoformans

A Wor1-Like Transcription Factor Is Essential for Virulence of Cryptococcus neoformans

Gti1/Pac2 transcription factors occur exclusively in fungi and their roles vary according to species, including regulating morphological transition and virulence, mating and secondary metabolism. Many of these functions are important for fungal pathogenesis. We therefore hypothesized that one of the...

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Bibliographic Details
Main Authors: Hugo Costa Paes, Lorena da Silveira Derengowski, Luisa Defranco Ferreira Peconick, Patrícia Albuquerque, Georgios Joannis Pappas, André Moraes Nicola, Fabiana Brandão Alves Silva, Marcelo Afonso Vallim, J. Andrew Alspaugh, Maria Sueli Soares Felipe, Larissa Fernandes
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-11-01
Series:Frontiers in Cellular and Infection Microbiology
Subjects:
Cryptococcus neoformans
capsule
cytokinesis
virulence
transcription factor
Online Access:https://www.frontiersin.org/article/10.3389/fcimb.2018.00369/full

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