Single Cell Transcriptomics: Methods and Applications

Single Cell Transcriptomics: Methods and Applications

Traditionally, gene expression measurements were performed on bulk samples containing populations of thousands of cells. Recent advances in genomic technology have made it possible to measure gene expression in hundreds of individual cells at a time. As a result, cellular properties that were previo...

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Bibliographic Details
Main Authors: Itamar eKanter, Tomer eKalisky
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-03-01
Series:Frontiers in Oncology
Subjects:
Gene Expression
qPCR
fish
single cell
RNA sequencing
Online Access:http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00053/full
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spelling doaj-f649c878e850412a811036ef14e6f3b52020-11-24T23:15:00ZengFrontiers Media S.A.Frontiers in Oncology2234-943X2015-03-01510.3389/fonc.2015.00053129637Single Cell Transcriptomics: Methods and ApplicationsItamar eKanter0Tomer eKalisky1Bar-Ilan universityBar-Ilan universityTraditionally, gene expression measurements were performed on bulk samples containing populations of thousands of cells. Recent advances in genomic technology have made it possible to measure gene expression in hundreds of individual cells at a time. As a result, cellular properties that were previously masked in bulk measurements can now be observed directly. In this review we will survey emerging technologies for single cell transcriptomics, and describe how they are used to study complex disease such as cancer, as well as other biological phenomena such as tissue regeneration, embryonic development, and immune response.http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00053/fullGene ExpressionqPCRfishsingle cellRNA sequencing
collection DOAJ
language English
format Article
sources DOAJ
author Itamar eKanter
Tomer eKalisky
spellingShingle Itamar eKanter
Tomer eKalisky
Single Cell Transcriptomics: Methods and Applications
Frontiers in Oncology
Gene Expression
qPCR
fish
single cell
RNA sequencing
author_facet Itamar eKanter
Tomer eKalisky
author_sort Itamar eKanter
title Single Cell Transcriptomics: Methods and Applications
title_short Single Cell Transcriptomics: Methods and Applications
title_full Single Cell Transcriptomics: Methods and Applications
title_fullStr Single Cell Transcriptomics: Methods and Applications
title_full_unstemmed Single Cell Transcriptomics: Methods and Applications
title_sort single cell transcriptomics: methods and applications
publisher Frontiers Media S.A.
series Frontiers in Oncology
issn 2234-943X
publishDate 2015-03-01
description Traditionally, gene expression measurements were performed on bulk samples containing populations of thousands of cells. Recent advances in genomic technology have made it possible to measure gene expression in hundreds of individual cells at a time. As a result, cellular properties that were previously masked in bulk measurements can now be observed directly. In this review we will survey emerging technologies for single cell transcriptomics, and describe how they are used to study complex disease such as cancer, as well as other biological phenomena such as tissue regeneration, embryonic development, and immune response.
topic Gene Expression
qPCR
fish
single cell
RNA sequencing
url http://journal.frontiersin.org/Journal/10.3389/fonc.2015.00053/full
work_keys_str_mv AT itamarekanter singlecelltranscriptomicsmethodsandapplications
AT tomerekalisky singlecelltranscriptomicsmethodsandapplications
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