Evaluation of Febrile Neutropenic Attacks

• Main Authors: Nebahat DİKİCİ, Onur URAL
• Format: Article
• Language: English
• Published: Bilimsel Tip Yayinevi 2002-09-01
• Series: Flora Infeksiyon Hastalıkları ve Klinik Mikrobiyoloji Dergisi
• Subjects: Febrile neutropenia; Infection; Treatment
• Online Access: http://www.floradergisi.org/getFileContent.aspx?op=REDPDF&file_name=2002-7-3-185-190.pdf

In this study, origin of infection, therapeutic protocols, success and mortality rate of therapy were investigated in febrile neutropenic cases. Eighty-two febrile neutropenic attacks in 67 patients (42 male, 25 female) between age 2-82 years were evaluated in this study. Forty-one of the patients were diagnosed as leukemia, 9 as lymphoma, 8 as other hematological malignancies. No hematological malignancies were found at 9 patients. At the end of the examinations, microbiologically documented infection was reported in 35 (42.7%) patients, clinically defined infection was reported in 30 (36.6%), and fever of unknown origin was reported in 17 (20.7%) patients. There was no statistically significant difference between absolute neutrophil count and aetiology of fever (p> 0.05). 75.6% of patients were treated with combined therapy, 14.6% of patients with monotherapy and 9.8% of them were treated with different therapies. Success in treatment was achieved at 61 (88.4%) patients, 8 (11.6%) patients died.