The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML

The landscape of gene co-expression modules correlating with prognostic genetic abnormalities in AML

Abstract Background The heterogenous cytogenetic and molecular variations were harbored by AML patients, some of which are related with AML pathogenesis and clinical outcomes. We aimed to uncover the intrinsic expression profiles correlating with prognostic genetic abnormalities by WGCNA. Methods We...

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Bibliographic Details
Main Authors: Chao Guo, Ya-yue Gao, Qian-qian Ju, Chun-xia Zhang, Ming Gong, Zhen-ling Li
Format: Article
Language:English
Published: BMC 2021-05-01
Series:Journal of Translational Medicine
Subjects:
Acute myeloid leukemia
Weighted co-expression network analysis
Prognostic signature
Online Access:https://doi.org/10.1186/s12967-021-02914-2

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