Differential Signaling During Macropinocytosis in Response to M-CSF and PMA in Macrophages

Differential Signaling During Macropinocytosis in Response to M-CSF and PMA in Macrophages

The cellular movements that construct a macropinosome have a corresponding sequence of chemical transitions in the cup-shaped region of plasma membrane that becomes the macropinosome. To determine the relative positions of type I phosphatidylinositol 3-kinase (PI3K) and phospholipase C (PLC) in this...

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Bibliographic Details
Main Authors: Sei eYoshida, Isabella eGaeta, Regina ePacitto, Lydia eKrienke, Olivia eAlge, Brian eGregorka, Joel A Swanson
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-01-01
Series:Frontiers in Physiology
Subjects:
Protein Kinase C
Ras
phospholipase C
diacylglycerol
macropinocytosis
PIP3
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphys.2015.00008/full

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