Intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleeding
Immunoglobulin light‐chain (AL) amyloidosis is a monoclonal plasma cell neoplasm that has a tendency to bleed easily. However, the potential risks of transbronchial biopsy in such cases have not been fully proven. Here, we report a case of parotid and intrathoracic AL amyloid tumors that presented a...
Main Authors: | , , , , , , , , , |
---|---|
Format: | Article |
Language: | English |
Published: |
Wiley
2019-10-01
|
Series: | Thoracic Cancer |
Subjects: | |
Online Access: | https://doi.org/10.1111/1759-7714.13159 |
id |
doaj-f68a87343ff04512bc404c22ab4285b2 |
---|---|
record_format |
Article |
spelling |
doaj-f68a87343ff04512bc404c22ab4285b22020-11-25T01:29:29ZengWileyThoracic Cancer1759-77061759-77142019-10-0110102026203010.1111/1759-7714.13159Intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleedingHiromi Tomono0Hiroshi Soda1Yuichi Fukuda2Yasuhiro Tanaka3Sawana Ono4Midori Shimada5Keisuke Iwasaki6Masashi Hisanaga7Hiroyuki Yamaguchi8Hiroshi Mukae9Department of Respiratory Medicine Sasebo City General Hospital Nagasaki JapanDepartment of Respiratory Medicine Sasebo City General Hospital Nagasaki JapanDepartment of Respiratory Medicine Sasebo City General Hospital Nagasaki JapanDepartment of Respiratory Medicine Sasebo City General Hospital Nagasaki JapanDepartment of Respiratory Medicine Sasebo City General Hospital Nagasaki JapanDepartment of Respiratory Medicine Sasebo City General Hospital Nagasaki JapanDepartment of Pathology Sasebo City General Hospital Nagasaki JapanDepartment of Otolaryngology Sasebo City General Hospital Nagasaki JapanDepartment of Respiratory Medicine Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanDepartment of Respiratory Medicine Nagasaki University Graduate School of Biomedical Sciences Nagasaki JapanImmunoglobulin light‐chain (AL) amyloidosis is a monoclonal plasma cell neoplasm that has a tendency to bleed easily. However, the potential risks of transbronchial biopsy in such cases have not been fully proven. Here, we report a case of parotid and intrathoracic AL amyloid tumors that presented as endobronchial protrusions that bled easily. Bronchoscopy under conventional white light and narrow band imaging revealed yellowish multinodular protrusions, in which irregular tortuous or dotted vessels were observed. Unexpectedly, biopsy of the lesion resulted in persistent bleeding. The biopsy specimen showed a large amount of amyloid deposition and calcification directly under the bronchial epithelium, as well as amyloid deposits in the blood vessel walls. In patients suspected to have amyloidosis, the presence of yellowish multinodular endobronchial protrusions, particularly with irregular vascularity, should prompt careful attention to avoid fatal postprocedural bleeding.https://doi.org/10.1111/1759-7714.13159Amyloidosisbleedingbronchoscopynarrow band imaging |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Hiromi Tomono Hiroshi Soda Yuichi Fukuda Yasuhiro Tanaka Sawana Ono Midori Shimada Keisuke Iwasaki Masashi Hisanaga Hiroyuki Yamaguchi Hiroshi Mukae |
spellingShingle |
Hiromi Tomono Hiroshi Soda Yuichi Fukuda Yasuhiro Tanaka Sawana Ono Midori Shimada Keisuke Iwasaki Masashi Hisanaga Hiroyuki Yamaguchi Hiroshi Mukae Intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleeding Thoracic Cancer Amyloidosis bleeding bronchoscopy narrow band imaging |
author_facet |
Hiromi Tomono Hiroshi Soda Yuichi Fukuda Yasuhiro Tanaka Sawana Ono Midori Shimada Keisuke Iwasaki Masashi Hisanaga Hiroyuki Yamaguchi Hiroshi Mukae |
author_sort |
Hiromi Tomono |
title |
Intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleeding |
title_short |
Intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleeding |
title_full |
Intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleeding |
title_fullStr |
Intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleeding |
title_full_unstemmed |
Intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleeding |
title_sort |
intrathoracic amyloid tumors that presented as yellowish multinodular endobronchial protrusions with irregular vascularity and easy bleeding |
publisher |
Wiley |
series |
Thoracic Cancer |
issn |
1759-7706 1759-7714 |
publishDate |
2019-10-01 |
description |
Immunoglobulin light‐chain (AL) amyloidosis is a monoclonal plasma cell neoplasm that has a tendency to bleed easily. However, the potential risks of transbronchial biopsy in such cases have not been fully proven. Here, we report a case of parotid and intrathoracic AL amyloid tumors that presented as endobronchial protrusions that bled easily. Bronchoscopy under conventional white light and narrow band imaging revealed yellowish multinodular protrusions, in which irregular tortuous or dotted vessels were observed. Unexpectedly, biopsy of the lesion resulted in persistent bleeding. The biopsy specimen showed a large amount of amyloid deposition and calcification directly under the bronchial epithelium, as well as amyloid deposits in the blood vessel walls. In patients suspected to have amyloidosis, the presence of yellowish multinodular endobronchial protrusions, particularly with irregular vascularity, should prompt careful attention to avoid fatal postprocedural bleeding. |
topic |
Amyloidosis bleeding bronchoscopy narrow band imaging |
url |
https://doi.org/10.1111/1759-7714.13159 |
work_keys_str_mv |
AT hiromitomono intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT hiroshisoda intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT yuichifukuda intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT yasuhirotanaka intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT sawanaono intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT midorishimada intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT keisukeiwasaki intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT masashihisanaga intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT hiroyukiyamaguchi intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding AT hiroshimukae intrathoracicamyloidtumorsthatpresentedasyellowishmultinodularendobronchialprotrusionswithirregularvascularityandeasybleeding |
_version_ |
1725096799403769856 |