Antigen-Specific Antibody Glycosylation Is Regulated via Vaccination.
Antibody effector functions, such as antibody-dependent cellular cytotoxicity, complement deposition, and antibody-dependent phagocytosis, play a critical role in immunity against multiple pathogens, particularly in the absence of neutralizing activity. Two modifications to the IgG constant domain (...
Main Authors: | Alison E Mahan, Madeleine F Jennewein, Todd Suscovich, Kendall Dionne, Jacquelynne Tedesco, Amy W Chung, Hendrik Streeck, Maria Pau, Hanneke Schuitemaker, Don Francis, Patricia Fast, Dagna Laufer, Bruce D Walker, Lindsey Baden, Dan H Barouch, Galit Alter |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2016-03-01
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Series: | PLoS Pathogens |
Online Access: | http://europepmc.org/articles/PMC4794126?pdf=render |
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