Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds

Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds

Alzheimer’s disease (AD) is a complex age-related neurodegenerative disease. In this review, we carefully detail amyloid-β metabolism and its role in AD. We also consider the various genetic animal models used to evaluate therapeutics. Finally, we consider the role of synthetic and plant-based compo...

Full description

Bibliographic Details
Main Authors: Sandeep Kumar Singh, Saurabh Srivastav, Amarish Kumar Yadav, Saripella Srikrishna, George Perry
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Oxidative Medicine and Cellular Longevity
Online Access:http://dx.doi.org/10.1155/2016/7361613
id doaj-f6c82b07999d47d9bb82753acda2cc9c
record_format Article
spelling doaj-f6c82b07999d47d9bb82753acda2cc9c2020-11-24T22:18:53ZengHindawi LimitedOxidative Medicine and Cellular Longevity1942-09001942-09942016-01-01201610.1155/2016/73616137361613Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal CompoundsSandeep Kumar Singh0Saurabh Srivastav1Amarish Kumar Yadav2Saripella Srikrishna3George Perry4Department of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, IndiaDepartment of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, IndiaDepartment of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, IndiaDepartment of Biochemistry, Faculty of Science, Banaras Hindu University, Varanasi 221 005, IndiaDepartment of Biology, The University of Texas at San Antonio, San Antonio, TX 78249, USAAlzheimer’s disease (AD) is a complex age-related neurodegenerative disease. In this review, we carefully detail amyloid-β metabolism and its role in AD. We also consider the various genetic animal models used to evaluate therapeutics. Finally, we consider the role of synthetic and plant-based compounds in therapeutics.http://dx.doi.org/10.1155/2016/7361613
collection DOAJ
language English
format Article
sources DOAJ
author Sandeep Kumar Singh
Saurabh Srivastav
Amarish Kumar Yadav
Saripella Srikrishna
George Perry
spellingShingle Sandeep Kumar Singh
Saurabh Srivastav
Amarish Kumar Yadav
Saripella Srikrishna
George Perry
Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds
Oxidative Medicine and Cellular Longevity
author_facet Sandeep Kumar Singh
Saurabh Srivastav
Amarish Kumar Yadav
Saripella Srikrishna
George Perry
author_sort Sandeep Kumar Singh
title Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds
title_short Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds
title_full Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds
title_fullStr Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds
title_full_unstemmed Overview of Alzheimer’s Disease and Some Therapeutic Approaches Targeting Aβ by Using Several Synthetic and Herbal Compounds
title_sort overview of alzheimer’s disease and some therapeutic approaches targeting aβ by using several synthetic and herbal compounds
publisher Hindawi Limited
series Oxidative Medicine and Cellular Longevity
issn 1942-0900
1942-0994
publishDate 2016-01-01
description Alzheimer’s disease (AD) is a complex age-related neurodegenerative disease. In this review, we carefully detail amyloid-β metabolism and its role in AD. We also consider the various genetic animal models used to evaluate therapeutics. Finally, we consider the role of synthetic and plant-based compounds in therapeutics.
url http://dx.doi.org/10.1155/2016/7361613
work_keys_str_mv AT sandeepkumarsingh overviewofalzheimersdiseaseandsometherapeuticapproachestargetingabbyusingseveralsyntheticandherbalcompounds
AT saurabhsrivastav overviewofalzheimersdiseaseandsometherapeuticapproachestargetingabbyusingseveralsyntheticandherbalcompounds
AT amarishkumaryadav overviewofalzheimersdiseaseandsometherapeuticapproachestargetingabbyusingseveralsyntheticandherbalcompounds
AT saripellasrikrishna overviewofalzheimersdiseaseandsometherapeuticapproachestargetingabbyusingseveralsyntheticandherbalcompounds
AT georgeperry overviewofalzheimersdiseaseandsometherapeuticapproachestargetingabbyusingseveralsyntheticandherbalcompounds
_version_ 1725781011909836800

Similar Items