CD109 plays a role in osteoclastogenesis.

Osteoclasts are large multinucleated cells that arise from the fusion of cells from the monocyte/macrophage lineage. Osteoclastogenesis is mediated by macrophage colony-stimulating factor (M-CSF) and receptor activator of nuclear factor-kB ligand (RANKL) and involves a complex multistep process that...

Full description

Bibliographic Details
Main Authors: Yongqiang Wang, Maayan Inger, Hongwei Jiang, Howard Tenenbaum, Michael Glogauer
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2013-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3625217?pdf=render