Effect of natural gel product on bovine dentin erosion in vitro

Objective: To evaluate the efficacy of Neem (Azadirachta indica) experimental gel for the prevention of erosive wear on bovine dentin, in vitro. Material and Methods: One hundred dentin blocks were allocated into 5 experimental groups (20 samples each): C (control group, without gel); CG (contr...

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Main Authors: Andre de Carvalho SALES-PERES, Juliane Avansini MARSICANO, Rudan Paraiso GARCIA, Moacir Rossi FORIM, Maria Fatima das Gracas Fernandes da SILVA, Silvia Helena de Carvalho SALES-PERES
Format: Article
Language:English
Published: University of São Paulo 2013-12-01
Series:Journal of Applied Oral Science
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572013000600597&lng=en&tlng=en
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spelling doaj-f6d94d21e4ee4b7ea416dca47bc9d9e52020-11-24T20:47:17ZengUniversity of São PauloJournal of Applied Oral Science1678-77652013-12-0121659760010.1590/1679-775720130242S1678-77572013000600597Effect of natural gel product on bovine dentin erosion in vitroAndre de Carvalho SALES-PERESJuliane Avansini MARSICANORudan Paraiso GARCIAMoacir Rossi FORIMMaria Fatima das Gracas Fernandes da SILVASilvia Helena de Carvalho SALES-PERESObjective: To evaluate the efficacy of Neem (Azadirachta indica) experimental gel for the prevention of erosive wear on bovine dentin, in vitro. Material and Methods: One hundred dentin blocks were allocated into 5 experimental groups (20 samples each): C (control group, without gel); CG (control group, only base gel); F (fluoride gel, 1.23% NaF; pH 4.1, Dentsply; Brazil); N (Neem gel, 10% neem extract; pH 4.1, manipulation); NF (Neem+fluoride gel, 10% Neem extract and 1.23% NaF; pH 4.1, manipulation). The blocks were stored in artificial saliva for 24 hours. After this, they were submitted to six alternating re- and demineralization cycles. The blocks were analyzed for wear (profilometry). The results were submitted to statistical analysis by ANOVA and Tukey tests (P<0.05). Results: The mean wear (±SD, µm) was shown as follows in groups: C (13.09±0.99), CG (10.60±1.99), F (10.90±1.44), N (12.68±1.13) and NF (10.84±1.65). All gels showed some preventive action when compared with control group. However, significant differences were found only between Neem+fluoride gel and fluoride gel. Conclusion: A single application of a neem-containing fluoride gel reduced dentin erosion, thus it is a possible alternative in reducing dental wear. Further research should investigate the action mechanism and the synergism between them.http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572013000600597&lng=en&tlng=enTooth erosionDemineralizationAzadirachta indicaTopical fluoridesDentin
collection DOAJ
language English
format Article
sources DOAJ
author Andre de Carvalho SALES-PERES
Juliane Avansini MARSICANO
Rudan Paraiso GARCIA
Moacir Rossi FORIM
Maria Fatima das Gracas Fernandes da SILVA
Silvia Helena de Carvalho SALES-PERES
spellingShingle Andre de Carvalho SALES-PERES
Juliane Avansini MARSICANO
Rudan Paraiso GARCIA
Moacir Rossi FORIM
Maria Fatima das Gracas Fernandes da SILVA
Silvia Helena de Carvalho SALES-PERES
Effect of natural gel product on bovine dentin erosion in vitro
Journal of Applied Oral Science
Tooth erosion
Demineralization
Azadirachta indica
Topical fluorides
Dentin
author_facet Andre de Carvalho SALES-PERES
Juliane Avansini MARSICANO
Rudan Paraiso GARCIA
Moacir Rossi FORIM
Maria Fatima das Gracas Fernandes da SILVA
Silvia Helena de Carvalho SALES-PERES
author_sort Andre de Carvalho SALES-PERES
title Effect of natural gel product on bovine dentin erosion in vitro
title_short Effect of natural gel product on bovine dentin erosion in vitro
title_full Effect of natural gel product on bovine dentin erosion in vitro
title_fullStr Effect of natural gel product on bovine dentin erosion in vitro
title_full_unstemmed Effect of natural gel product on bovine dentin erosion in vitro
title_sort effect of natural gel product on bovine dentin erosion in vitro
publisher University of São Paulo
series Journal of Applied Oral Science
issn 1678-7765
publishDate 2013-12-01
description Objective: To evaluate the efficacy of Neem (Azadirachta indica) experimental gel for the prevention of erosive wear on bovine dentin, in vitro. Material and Methods: One hundred dentin blocks were allocated into 5 experimental groups (20 samples each): C (control group, without gel); CG (control group, only base gel); F (fluoride gel, 1.23% NaF; pH 4.1, Dentsply; Brazil); N (Neem gel, 10% neem extract; pH 4.1, manipulation); NF (Neem+fluoride gel, 10% Neem extract and 1.23% NaF; pH 4.1, manipulation). The blocks were stored in artificial saliva for 24 hours. After this, they were submitted to six alternating re- and demineralization cycles. The blocks were analyzed for wear (profilometry). The results were submitted to statistical analysis by ANOVA and Tukey tests (P<0.05). Results: The mean wear (±SD, µm) was shown as follows in groups: C (13.09±0.99), CG (10.60±1.99), F (10.90±1.44), N (12.68±1.13) and NF (10.84±1.65). All gels showed some preventive action when compared with control group. However, significant differences were found only between Neem+fluoride gel and fluoride gel. Conclusion: A single application of a neem-containing fluoride gel reduced dentin erosion, thus it is a possible alternative in reducing dental wear. Further research should investigate the action mechanism and the synergism between them.
topic Tooth erosion
Demineralization
Azadirachta indica
Topical fluorides
Dentin
url http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-77572013000600597&lng=en&tlng=en
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