Phylogenetic Tree Inference: A Top-Down Approach to Track Tumor Evolution

Recently, an increasing number of studies sequence multiple biopsies of primary tumors, and even paired metastatic tumors to understand heterogeneity and the evolutionary trajectory of cancer progression. Although several algorithms are available to infer the phylogeny, most tools rely on accurate m...

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Bibliographic Details
Main Authors: Pin Wu, Linjun Hou, Yingdong Zhang, Liye Zhang
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-02-01
Series:Frontiers in Genetics
Subjects:
Online Access:https://www.frontiersin.org/article/10.3389/fgene.2019.01371/full

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