COMMON ALLERGENS FOR ALLERGIC PATIENTS IN ISFAHAN: A CLINICALLY - BASED STUDY

• Main Authors: E AKBARI HEDAYAT, A REZAEI
• Format: Article
• Language: English
• Published: Wolters Kluwer Medknow Publications 2000-03-01
• Series: Journal of Research in Medical Sciences
• Subjects: Allergens extracts, Skin tests, Allergic diseases, Cross-sectional study
• Online Access: http://journals.mui.ac.ir/jrms/article/view/3485

Introduction. Detection of the common allergens in any region is critical for prevention and treatment of allergic diseases. The objective of this study was to identify the common allergens causes of clinical symptoms in allergic patients in Isfahan.
 Methods. In this clinically-based cross-sectional study, 1077 patients with allergic diseases, underwent skin prick test with thirty extracts of allergens (Aestallergen Co.) at Asthma and Allergy Clinic of Issa Ibne Maryam (Isfahan) during 1999.
 Findings. Positive skin reactions were observed in 85 perdent (914) of patients. Reactions to weed, fungi, mite and tree were 48, 37, 35 and 30 percent, respectively. Reactions to grass, barn dust and cockroach are about 20 percent for each. Positive reactions to pollens were seen more in males (P>0. 05), whereas, positive reactions to mite, mould and cockroach were more seen in females (P>0.05). Reactions to moulds, pollens and barn dust seen in adults more than other age groups. Seventy percent of positive tests in patients with allergic rhinitis were related to pallens. In asthmatic patients reactions to pollens, mite, cockroach and moulds were 30, 38, 37 and 11 percent, respectively. In allergic skin disorders, positive tests to fungi, mite, pollens, cockroach and barn dust were 22, 18, 16, 12 and 10 percent, respectively. Negative responses seen in allergic skin disorders, asthma and allergic rhinitis were 36, 15 and 7 percent, respectively. Russian thistle and chenopodium among weeds; timothy and ray of grasses; willow and ash of trees, cladosporium in fungis were more common than other subtypes of these allergens. Pollen reactions were seen more in spring and summer, mould and mite reactions seen more in autumn and winter (P < 0.05).
 Conclusion. Avoidance of common allergens (russian thistle, chenopodium, timothy, willow, cladosporium, mite, cockroach, barn dust, nut) is highly needed for patients. Determination of these agents are useful for allergen extract productions. According to clinical datas of each patient, a limited number of extracts is suggested for skin test.