Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study
Objective The main purpose of this article is to define prognosis of pregnancies in epileptic women in Benin. Methods This was a case–control study that included 54 epileptic women who had at least one pregnancy matched to 162 controls on age, pregnancy term, and monitoring center. Information abou...
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doaj-f73666087d314064877dd9310c13a7a22021-02-02T04:40:14ZengThieme Medical and Scientific Publishers Pvt. Ltd.Journal of Neurosciences in Rural Practice0976-31470976-31552020-06-01110339540210.1055/s-0040-1709366Prognosis of Pregnancy in Epileptics in Benin: A Case–Control StudyThierry Adoukonou0Mendinatou Agbétou1Rachidi Imorou Sidi2Colombe Gnansounou3Donald Accrombessi4Yasmine Hounzangbe-Adoukonou5Dieudonné Gnonlonfoun6Salifou Kabibou7Josiane Angéline Tonato-Bagnan8Dismand Houinato9Department of Neurology, University of Parakou, Parakou, BeninDepartment of Neurology, University of Parakou, Parakou, BeninDepartment of Gynecology and Obstetrics, University of Parakou, Parakou, BeninClinic of Neurology, University Teaching Hospital of Parakou, Parakou, BeninClinic of Neurology, University Teaching Hospital of Parakou, Parakou, BeninDepartment of Gynecology and Obstetrics, University of Parakou, Parakou, BeninDepartment of Neurology, University of Abomey-Calavi, Cotonou, BeninDepartment of Gynecology and Obstetrics, University of Parakou, Parakou, BeninDepartment of Gynecology and Obstetrics, University of Abomey-Calavi, Cotonou, BeninDepartment of Neurology, University of Abomey-Calavi, Cotonou, BeninObjective The main purpose of this article is to define prognosis of pregnancies in epileptic women in Benin. Methods This was a case–control study that included 54 epileptic women who had at least one pregnancy matched to 162 controls on age, pregnancy term, and monitoring center. Information about epilepsy, treatment, pregnancy, and childbirth were collected. A logistic regression with odds ratio (OR) calculation was used to study the association. Results During pregnancy 22.22% of epileptic women experienced an increase in seizure frequency. Epileptics had more frequent miscarriages (OR: 1.84 [1.01–3.51]), more incidents during pregnancy (OR: 4.03 [1.04–15.60]), and were more often hospitalized (OR: 3.35 [1.46–7.69]) than women without epilepsy. They, more often, had premature children before 37 weeks of amenorrhea (OR: 2.10 [1.12–3.91]) and gave birth to low-birth-weight children (OR = 2.17 [1.00–4.76]). Conclusion Occurrence of a pregnancy in an epileptic woman in Benin is at risk and requires multidisciplinary monitoring by both neurologist and obstetrician to reduce complications.http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1709366epilepsypregnancyprognosisafrica |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Thierry Adoukonou Mendinatou Agbétou Rachidi Imorou Sidi Colombe Gnansounou Donald Accrombessi Yasmine Hounzangbe-Adoukonou Dieudonné Gnonlonfoun Salifou Kabibou Josiane Angéline Tonato-Bagnan Dismand Houinato |
spellingShingle |
Thierry Adoukonou Mendinatou Agbétou Rachidi Imorou Sidi Colombe Gnansounou Donald Accrombessi Yasmine Hounzangbe-Adoukonou Dieudonné Gnonlonfoun Salifou Kabibou Josiane Angéline Tonato-Bagnan Dismand Houinato Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study Journal of Neurosciences in Rural Practice epilepsy pregnancy prognosis africa |
author_facet |
Thierry Adoukonou Mendinatou Agbétou Rachidi Imorou Sidi Colombe Gnansounou Donald Accrombessi Yasmine Hounzangbe-Adoukonou Dieudonné Gnonlonfoun Salifou Kabibou Josiane Angéline Tonato-Bagnan Dismand Houinato |
author_sort |
Thierry Adoukonou |
title |
Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study |
title_short |
Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study |
title_full |
Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study |
title_fullStr |
Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study |
title_full_unstemmed |
Prognosis of Pregnancy in Epileptics in Benin: A Case–Control Study |
title_sort |
prognosis of pregnancy in epileptics in benin: a case–control study |
publisher |
Thieme Medical and Scientific Publishers Pvt. Ltd. |
series |
Journal of Neurosciences in Rural Practice |
issn |
0976-3147 0976-3155 |
publishDate |
2020-06-01 |
description |
Objective The main purpose of this article is to define prognosis of pregnancies in epileptic women in Benin.
Methods This was a case–control study that included 54 epileptic women who had at least one pregnancy matched to 162 controls on age, pregnancy term, and monitoring center. Information about epilepsy, treatment, pregnancy, and childbirth were collected. A logistic regression with odds ratio (OR) calculation was used to study the association.
Results During pregnancy 22.22% of epileptic women experienced an increase in seizure frequency. Epileptics had more frequent miscarriages (OR: 1.84 [1.01–3.51]), more incidents during pregnancy (OR: 4.03 [1.04–15.60]), and were more often hospitalized (OR: 3.35 [1.46–7.69]) than women without epilepsy. They, more often, had premature children before 37 weeks of amenorrhea (OR: 2.10 [1.12–3.91]) and gave birth to low-birth-weight children (OR = 2.17 [1.00–4.76]).
Conclusion Occurrence of a pregnancy in an epileptic woman in Benin is at risk and requires multidisciplinary monitoring by both neurologist and obstetrician to reduce complications. |
topic |
epilepsy pregnancy prognosis africa |
url |
http://www.thieme-connect.de/DOI/DOI?10.1055/s-0040-1709366 |
work_keys_str_mv |
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