The reciprocal regulation between host tissue and immune cells in pancreatic ductal adenocarcinoma: new insights and therapeutic implications

The reciprocal regulation between host tissue and immune cells in pancreatic ductal adenocarcinoma: new insights and therapeutic implications

Abstract Pancreatic ductal adenocarcinoma (PDAC) is the fourth leading cause of cancer-related death and is one of the most difficult-to-treat cancers. Surgical resection and adjuvant therapy have limited effects on the overall survival of PDAC patients. PDAC exhibits an immunosuppressive microenvir...

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Bibliographic Details
Main Authors: Xiaomeng Liu, Jin Xu, Bo Zhang, Jiang Liu, Chen Liang, Qingcai Meng, Jie Hua, Xianjun Yu, Si Shi
Format: Article
Language:English
Published: BMC 2019-12-01
Series:Molecular Cancer
Subjects:
Pancreatic ductal adenocarcinoma
Immune infiltrate
Stromal cells
Immunotherapy
Online Access:https://doi.org/10.1186/s12943-019-1117-9

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