Oxidative stress, metabolomics profiling, and mechanism of local anesthetic induced cell death in yeast

Oxidative stress, metabolomics profiling, and mechanism of local anesthetic induced cell death in yeast

The World Health Organization designates lidocaine as an essential medicine in healthcare, greatly increasing the probability of human exposure. Its use has been associated with ROS generation and neurotoxicity. Physiological and metabolomic alterations, and genetics leading to the clinically observ...

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Bibliographic Details
Main Authors: Cory H.T. Boone, Ryan A. Grove, Dana Adamcova, Javier Seravalli, Jiri Adamec
Format: Article
Language:English
Published: Elsevier 2017-08-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S221323171630355X

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