Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance

The paper characterizes the neuropathological aspects of cerebral amyloid angiopathy (CAA) and its pathogenesis. It presents in detail the current neuroimaging markers of CAA and their neuropathological correlates. The phenotypic heterogeneity of the disease and its main clinical manifestations are...

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Main Authors:	A. A. Kulesh, V. E. Drobakha, V. V. Shestakov
Format:	Article
Language:	Russian
Published:	IMA-PRESS LLC 2018-11-01
Series:	Nevrologiâ, Nejropsihiatriâ, Psihosomatika
Subjects:	cerebral amyloid angiopathy microbleeding cortical superficial siderosis hemorrhagic stroke
Online Access:	https://nnp.ima-press.net/nnp/article/view/942

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spelling	doaj-f767fa45689245b0bf41dad1dcf8d2c22021-07-29T08:58:39ZrusIMA-PRESS LLCNevrologiâ, Nejropsihiatriâ, Psihosomatika2074-27112310-13422018-11-0110341110.14412/2074-2711-2018-3-4-11756Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significanceA. A. Kulesh0V. E. Drobakha1V. V. Shestakov2Acad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia, PermAcad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia, PermAcad. E.A. Vagner Perm State Medical University, Ministry of Health of Russia, PermThe paper characterizes the neuropathological aspects of cerebral amyloid angiopathy (CAA) and its pathogenesis. It presents in detail the current neuroimaging markers of CAA and their neuropathological correlates. The phenotypic heterogeneity of the disease and its main clinical manifestations are considered; the updated Boston diagnostic criteria are formulated. The issues of intracerebral hemorrhages, cerebral microbleeding, and cortical superficial siderosis, which are associated with CAA, are elucidated in detail. CAA is noted to be of clinical significance for the determination of therapeutic policy in hemorrhagic stroke, systemic thrombolytic therapy, and cognitive impairment.https://nnp.ima-press.net/nnp/article/view/942cerebral amyloid angiopathymicrobleedingcortical superficial siderosishemorrhagic stroke
collection	DOAJ
language	Russian
format	Article
sources	DOAJ
author	A. A. Kulesh V. E. Drobakha V. V. Shestakov
spellingShingle	A. A. Kulesh V. E. Drobakha V. V. Shestakov Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance Nevrologiâ, Nejropsihiatriâ, Psihosomatika cerebral amyloid angiopathy microbleeding cortical superficial siderosis hemorrhagic stroke
author_facet	A. A. Kulesh V. E. Drobakha V. V. Shestakov
author_sort	A. A. Kulesh
title	Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance
title_short	Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance
title_full	Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance
title_fullStr	Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance
title_full_unstemmed	Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance
title_sort	hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance
publisher	IMA-PRESS LLC
series	Nevrologiâ, Nejropsihiatriâ, Psihosomatika
issn	2074-2711 2310-1342
publishDate	2018-11-01
description	The paper characterizes the neuropathological aspects of cerebral amyloid angiopathy (CAA) and its pathogenesis. It presents in detail the current neuroimaging markers of CAA and their neuropathological correlates. The phenotypic heterogeneity of the disease and its main clinical manifestations are considered; the updated Boston diagnostic criteria are formulated. The issues of intracerebral hemorrhages, cerebral microbleeding, and cortical superficial siderosis, which are associated with CAA, are elucidated in detail. CAA is noted to be of clinical significance for the determination of therapeutic policy in hemorrhagic stroke, systemic thrombolytic therapy, and cognitive impairment.
topic	cerebral amyloid angiopathy microbleeding cortical superficial siderosis hemorrhagic stroke
url	https://nnp.ima-press.net/nnp/article/view/942
work_keys_str_mv	AT aakulesh hemorrhagicmanifestationsofcerebralamyloidangiopathyfrompathogenesistoclinicalsignificance AT vedrobakha hemorrhagicmanifestationsofcerebralamyloidangiopathyfrompathogenesistoclinicalsignificance AT vvshestakov hemorrhagicmanifestationsofcerebralamyloidangiopathyfrompathogenesistoclinicalsignificance
_version_	1721250661803229184

Hemorrhagic manifestations of cerebral amyloid angiopathy: from pathogenesis to clinical significance

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