Advances of oligodendrocytes and myelination involving in learning and memory
Neuronal activity and learning can regulate the adult oligodendrogenesis. However, functional significance of this regulation remains not fully clear. Here, we reviewed the most recent progresses in the field of oligodendrocytes and myelination involved in learning and memory. Firstly, we introduce...
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Editorial Office of Journal of Third Military Medical University
2020-05-01
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doaj-f7716eddf7d64da28a290602820a616c2021-05-09T04:17:57ZzhoEditorial Office of Journal of Third Military Medical UniversityDi-san junyi daxue xuebao1000-54042020-05-0142988789010.16016/j.1000-5404.202002018Advances of oligodendrocytes and myelination involving in learning and memory YAO Zhongxiang0HU Bo1Department of Physiology, College of Basic Medical Sciences, Army Medical University (Third Military Medical University), Chongqing, 400038, China Department of Physiology, College of Basic Medical Sciences, Army Medical University (Third Military Medical University), Chongqing, 400038, China Neuronal activity and learning can regulate the adult oligodendrogenesis. However, functional significance of this regulation remains not fully clear. Here, we reviewed the most recent progresses in the field of oligodendrocytes and myelination involved in learning and memory. Firstly, we introduce the evidence demonstrating that the oligodendrocytes and myelination are involved in learning and memory. Secondly, we show the gene expression changes of oligodendrocytes, which are closely associated with the progression of Alzheimer's disease. Third, we introduce a few of drug administration which are used to promote oligodendroglial differentiation and myelination and to rescue impairment of learning and memory. At last, we analyze the shortage of current research and propose the trend for future researches.http://aammt.tmmu.edu.cn/Upload/rhtml/202002018.htmoligodendrocytemyelinationlearning and memoryalzheimer's diseasepharmacotherapycognitive impairment |
collection |
DOAJ |
language |
zho |
format |
Article |
sources |
DOAJ |
author |
YAO Zhongxiang HU Bo |
spellingShingle |
YAO Zhongxiang HU Bo Advances of oligodendrocytes and myelination involving in learning and memory Di-san junyi daxue xuebao oligodendrocyte myelination learning and memory alzheimer's disease pharmacotherapy cognitive impairment |
author_facet |
YAO Zhongxiang HU Bo |
author_sort |
YAO Zhongxiang |
title |
Advances of oligodendrocytes and myelination involving in learning and memory |
title_short |
Advances of oligodendrocytes and myelination involving in learning and memory |
title_full |
Advances of oligodendrocytes and myelination involving in learning and memory |
title_fullStr |
Advances of oligodendrocytes and myelination involving in learning and memory |
title_full_unstemmed |
Advances of oligodendrocytes and myelination involving in learning and memory |
title_sort |
advances of oligodendrocytes and myelination involving in learning and memory |
publisher |
Editorial Office of Journal of Third Military Medical University |
series |
Di-san junyi daxue xuebao |
issn |
1000-5404 |
publishDate |
2020-05-01 |
description |
Neuronal activity and learning can regulate the adult oligodendrogenesis. However, functional significance of this regulation remains not fully clear. Here, we reviewed the most recent progresses in the field of oligodendrocytes and myelination involved in learning and memory. Firstly, we introduce the evidence demonstrating that the oligodendrocytes and myelination are involved in learning and memory. Secondly, we show the gene expression changes of oligodendrocytes, which are closely associated with the progression of Alzheimer's disease. Third, we introduce a few of drug administration which are used to promote oligodendroglial differentiation and myelination and to rescue impairment of learning and memory. At last, we analyze the shortage of current research and propose the trend for future researches. |
topic |
oligodendrocyte myelination learning and memory alzheimer's disease pharmacotherapy cognitive impairment |
url |
http://aammt.tmmu.edu.cn/Upload/rhtml/202002018.htm |
work_keys_str_mv |
AT yaozhongxiang advancesofoligodendrocytesandmyelinationinvolvinginlearningandmemory AT hubo advancesofoligodendrocytesandmyelinationinvolvinginlearningandmemory |
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1721454885062311936 |