The genetic interpretation of area under the ROC curve in genomic profiling.
Genome-wide association studies in human populations have facilitated the creation of genomic profiles which combine the effects of many associated genetic variants to predict risk of disease. The area under the receiver operator characteristic (ROC) curve is a well established measure for determini...
Main Authors: | Naomi R Wray, Jian Yang, Michael E Goddard, Peter M Visscher |
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Format: | Article |
Language: | English |
Published: |
Public Library of Science (PLoS)
2010-02-01
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Series: | PLoS Genetics |
Online Access: | http://europepmc.org/articles/PMC2829056?pdf=render |
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