Behavioral phenotyping of mice deficient for tumor necrosis factor

Behavioral phenotyping of mice deficient for tumor necrosis factor

The tumor necrosis factor (TNF) is a cytokine exerting both homeostatic and pathophysiological roles in the central nervous system (CNS). It has been demonstrated that TNF plays roles in such diseases as Alzheimer’s disease, Parkinson’s disease and multiple sclerosis. Nevertheless, the role of TNF i...

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Bibliographic Details
Main Authors: D. V. Fursenko, N. V. Khotskin, V. A. Kulikov, A. V. Kulikov
Format: Article
Language:English
Published: Institute of Cytology and Genetics of Siberian Branch of the Russian Academy of Sciences 2015-12-01
Series:Vavilovskij Žurnal Genetiki i Selekcii
Subjects:
tumor necrosis factor
knockout mice
openfield
elevated plus-maze
forced-swim test
Online Access:https://vavilov.elpub.ru/jour/article/view/424

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