The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds

New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chr...

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Main Authors:	Abu Bakar Mohamad, Abdul Amir H. Kadhum, Ahmed A. Al-Amiery, Ahmed Y. Musa
Format:	Article
Language:	English
Published:	MDPI AG 2011-08-01
Series:	Molecules
Subjects:	coumarin ethyl bromoacetate phosphorous oxychloride 1,3,4-thiadiazole thiosemicarbazide umbelliferone
Online Access:	http://www.mdpi.com/1420-3049/16/8/6833/

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spelling	doaj-f79945d548fc41b5a4f7c4c8e43e16f52020-11-24T22:14:42ZengMDPI AGMolecules1420-30492011-08-011686833684310.3390/molecules16086833The Use of Umbelliferone in the Synthesis of New Heterocyclic CompoundsAbu Bakar MohamadAbdul Amir H. KadhumAhmed A. Al-AmieryAhmed Y. MusaNew coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (8) and 7-[(5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)methoxy]-2H-chromen-2-one (9) were prepared starting from the natural compound umbelliferone (1). The newly synthesized compounds were characterized by elemental analysis and spectral studies (IR, 1H-NMR and 13C-NMR).http://www.mdpi.com/1420-3049/16/8/6833/coumarinethyl bromoacetatephosphorous oxychloride1,3,4-thiadiazolethiosemicarbazideumbelliferone
collection	DOAJ
language	English
format	Article
sources	DOAJ
author	Abu Bakar Mohamad Abdul Amir H. Kadhum Ahmed A. Al-Amiery Ahmed Y. Musa
spellingShingle	Abu Bakar Mohamad Abdul Amir H. Kadhum Ahmed A. Al-Amiery Ahmed Y. Musa The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds Molecules coumarin ethyl bromoacetate phosphorous oxychloride 1,3,4-thiadiazole thiosemicarbazide umbelliferone
author_facet	Abu Bakar Mohamad Abdul Amir H. Kadhum Ahmed A. Al-Amiery Ahmed Y. Musa
author_sort	Abu Bakar Mohamad
title	The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_short	The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_full	The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_fullStr	The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_full_unstemmed	The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds
title_sort	use of umbelliferone in the synthesis of new heterocyclic compounds
publisher	MDPI AG
series	Molecules
issn	1420-3049
publishDate	2011-08-01
description	New coumarin derivatives, namely 7-[(5-amino-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (4), 5-[(2-oxo-2H-chromen-7-yloxy)methyl]-1,3,4-thiadiazol-2(3H)-one (5), 2-[2-(2-oxo-2H-chromen-7-yloxy)acetyl]-N-phenylhydrazinecarbothioamide (7), 7-[(5-(phenylamino)-1,3,4-thiadiazol-2-yl)methoxy]-2H-chromen-2-one (8) and 7-[(5-mercapto-4-phenyl-4H-1,2,4-triazol-3-yl)methoxy]-2H-chromen-2-one (9) were prepared starting from the natural compound umbelliferone (1). The newly synthesized compounds were characterized by elemental analysis and spectral studies (IR, 1H-NMR and 13C-NMR).
topic	coumarin ethyl bromoacetate phosphorous oxychloride 1,3,4-thiadiazole thiosemicarbazide umbelliferone
url	http://www.mdpi.com/1420-3049/16/8/6833/
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The Use of Umbelliferone in the Synthesis of New Heterocyclic Compounds

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