Treatment of autosomal recessive and autosomal dominant polycystic kidney disease

Treatment of autosomal recessive and autosomal dominant polycystic kidney disease

The article reflects the genetic variants of polycystic kidney disease, describes the modern strategy for the treatment of polycystic kidney disease in children and adults. The authors present the results of clinical trials of vasopressin V2 receptor antagonists (tolvaptan, liksivaptan), a multi-kin...

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Main Authors: E. F. Andreeva, N. D. Savenkova
Format: Article
Language:Russian
Published: Ltd. “The National Academy of Pediatric Science and Innovation” 2019-05-01
Series:Rossijskij Vestnik Perinatologii i Pediatrii
Subjects:
children
polycystic kidney disease
treatment
prognosis
Online Access:https://www.ped-perinatology.ru/jour/article/view/852
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spelling doaj-f7a5e4e43d4f424787efb708f265e4282021-07-28T16:27:50ZrusLtd. “The National Academy of Pediatric Science and Innovation”Rossijskij Vestnik Perinatologii i Pediatrii1027-40652500-22282019-05-01642222910.21508/1027-4065-2019-64-2-22-29713Treatment of autosomal recessive and autosomal dominant polycystic kidney diseaseE. F. Andreeva0N. D. Savenkova1Saint-Petersburg State Pediatric Medical UniversitySaint-Petersburg State Pediatric Medical UniversityThe article reflects the genetic variants of polycystic kidney disease, describes the modern strategy for the treatment of polycystic kidney disease in children and adults. The authors present the results of clinical trials of vasopressin V2 receptor antagonists (tolvaptan, liksivaptan), a multi-kinase inhibitor (tezevatinib), somatostatin analogues (lankreotide, octreotide), statins (pravastatin), mTOR inhibitors (everolimus, sirolimus), metformin in patients with autosomal recessive and autosomal polycystic kidney disease. The authors discuss the factors determining the prognosis and outcome of these diseases.https://www.ped-perinatology.ru/jour/article/view/852childrenpolycystic kidney diseasetreatmentprognosis
collection DOAJ
language Russian
format Article
sources DOAJ
author E. F. Andreeva
N. D. Savenkova
spellingShingle E. F. Andreeva
N. D. Savenkova
Treatment of autosomal recessive and autosomal dominant polycystic kidney disease
Rossijskij Vestnik Perinatologii i Pediatrii
children
polycystic kidney disease
treatment
prognosis
author_facet E. F. Andreeva
N. D. Savenkova
author_sort E. F. Andreeva
title Treatment of autosomal recessive and autosomal dominant polycystic kidney disease
title_short Treatment of autosomal recessive and autosomal dominant polycystic kidney disease
title_full Treatment of autosomal recessive and autosomal dominant polycystic kidney disease
title_fullStr Treatment of autosomal recessive and autosomal dominant polycystic kidney disease
title_full_unstemmed Treatment of autosomal recessive and autosomal dominant polycystic kidney disease
title_sort treatment of autosomal recessive and autosomal dominant polycystic kidney disease
publisher Ltd. “The National Academy of Pediatric Science and Innovation”
series Rossijskij Vestnik Perinatologii i Pediatrii
issn 1027-4065
2500-2228
publishDate 2019-05-01
description The article reflects the genetic variants of polycystic kidney disease, describes the modern strategy for the treatment of polycystic kidney disease in children and adults. The authors present the results of clinical trials of vasopressin V2 receptor antagonists (tolvaptan, liksivaptan), a multi-kinase inhibitor (tezevatinib), somatostatin analogues (lankreotide, octreotide), statins (pravastatin), mTOR inhibitors (everolimus, sirolimus), metformin in patients with autosomal recessive and autosomal polycystic kidney disease. The authors discuss the factors determining the prognosis and outcome of these diseases.
topic children
polycystic kidney disease
treatment
prognosis
url https://www.ped-perinatology.ru/jour/article/view/852
work_keys_str_mv AT efandreeva treatmentofautosomalrecessiveandautosomaldominantpolycystickidneydisease
AT ndsavenkova treatmentofautosomalrecessiveandautosomaldominantpolycystickidneydisease
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