MyD88 signalling is critical in the development of pancreatic cancer cachexia
Abstract Background Up to 80% of pancreatic cancer patients suffer from cachexia, a devastating condition that exacerbates underlying disease, reduces quality of life, and increases treatment complications and mortality. Tumour‐induced inflammation is linked to this multifactorial wasting syndrome,...
Main Authors: | Xinxia Zhu, Kevin G. Burfeind, Katherine A. Michaelis, Theodore P. Braun, Brennan Olson, Katherine R. Pelz, Terry K. Morgan, Daniel L. Marks |
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Format: | Article |
Language: | English |
Published: |
Wiley
2019-04-01
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Series: | Journal of Cachexia, Sarcopenia and Muscle |
Subjects: | |
Online Access: | https://doi.org/10.1002/jcsm.12377 |
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