A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses

A comprehensive analysis and resource to use CRISPR-Cas13 for broad-spectrum targeting of RNA viruses

Summary: The coronavirus disease 2019 (COVID-19) pandemic caused by severe acute respiratory syndrome-coronavirus-2 (SARS-CoV-2) and variants has led to significant mortality. We recently reported that an RNA-targeting CRISPR-Cas13 system, called prophylactic antiviral CRISPR in human cells (PAC-MAN...

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Bibliographic Details
Main Authors: Xueqiu Lin, Yanxia Liu, Augustine Chemparathy, Tara Pande, Marie La Russa, Lei S. Qi
Format: Article
Language:English
Published: Elsevier 2021-04-01
Series:Cell Reports Medicine
Subjects:
CRISPR
Cas13
SARS-CoV-2
COVID-19
antiviral
RNA virus
Online Access:http://www.sciencedirect.com/science/article/pii/S2666379121000616

Internet

http://www.sciencedirect.com/science/article/pii/S2666379121000616

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