A 6-year Retrospective Epidemiologic Study of Pediatric Pneumococcal Pneumonia in Taiwan
Community-acquired pneumonia (CAP) is one of the most common diseases during childhood, and its features vary between countries. Death from CAP is rare in industrialized countries, but it is the leading cause of mortality in developing countries. The purpose of this study was to determine the epidem...
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doaj-f8053dd3cd594a0bafb17218ac8140f72020-11-24T22:35:19ZengElsevierJournal of the Formosan Medical Association0929-66462008-12-011071294595110.1016/S0929-6646(09)60018-8A 6-year Retrospective Epidemiologic Study of Pediatric Pneumococcal Pneumonia in TaiwanYi-Chuan Huang0Yu-Huai Ho1Yu-Chia Hsieh2Hsiao-Chuan Lin3Kao-Pin Hwang4Luan-Yin Chang5Li-Min Huang6Division of Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, TaiwanDivision of Infectious Disease, Department of Internal Medicine, Buddhist Tzu Chi General Hospital, Hualien, TaiwanDivision of Pediatric Infectious Diseases, Department of Pediatrics, Chang Gung Children's Hospital, Chang Gung University College of Medicine, Taipei, TaiwanDepartment of Pediatrics, China Medical University Hospital, Taichung, TaiwanDivision of Infectious Diseases, Department of Pediatrics, Chang Gung Memorial Hospital-Kaohsiung Medical Center, Chang Gung University College of Medicine, Kaohsiung, TaiwanDepartment of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanDepartment of Pediatrics, National Taiwan University Hospital, Taipei, TaiwanCommunity-acquired pneumonia (CAP) is one of the most common diseases during childhood, and its features vary between countries. Death from CAP is rare in industrialized countries, but it is the leading cause of mortality in developing countries. The purpose of this study was to determine the epidemiology and morbidity of pneumococcal CAP (PCAP) in children hospitalized with pneumonia in Taiwan. Methods: We retrospectively screened the medical records of 12,914 children hospitalized with pneumonia at four hospitals in Taiwan from 2000 to 2005. This included a suspected PCAP group (2350 patients) and a group with likely/definite pneumococcal pneumonia (PP group, 901 patients). Results: From 2000, the frequency of suspected PCAP increased gradually every year, and peaked in 2003 (22.14%); while the proportion of likely/definite PP was highest in 2004 (9.75%). The likely/definite PP group accounted for 6.98% of the hospitalized pneumonia patients from 2000 to 2005. Of children hospitalized with pneumonia, 17.9% of the suspected PCAP group and 21.3% of the PP group were admitted to the intensive care unit (ICU). Twenty-three patients died (14 in the PCAP and 9 in the PP groups) and nine (5 in the PCAP and 4 in the PP groups) were discharged with sequelae. Conclusion: Our results indicate that children hospitalized with PCAP are common in Taiwan. About 20% of these children need ICU admissions, and some still have a poor outcome. Effective immunization programs with pneumococcal conjugate vaccine are needed for disease control and prevention.http://www.sciencedirect.com/science/article/pii/S0929664609600188bacterialcommunity acquired pneumoniaepidemiological studyimmunizationStreptococcus pneumoniae |
collection |
DOAJ |
language |
English |
format |
Article |
sources |
DOAJ |
author |
Yi-Chuan Huang Yu-Huai Ho Yu-Chia Hsieh Hsiao-Chuan Lin Kao-Pin Hwang Luan-Yin Chang Li-Min Huang |
spellingShingle |
Yi-Chuan Huang Yu-Huai Ho Yu-Chia Hsieh Hsiao-Chuan Lin Kao-Pin Hwang Luan-Yin Chang Li-Min Huang A 6-year Retrospective Epidemiologic Study of Pediatric Pneumococcal Pneumonia in Taiwan Journal of the Formosan Medical Association bacterial community acquired pneumonia epidemiological study immunization Streptococcus pneumoniae |
author_facet |
Yi-Chuan Huang Yu-Huai Ho Yu-Chia Hsieh Hsiao-Chuan Lin Kao-Pin Hwang Luan-Yin Chang Li-Min Huang |
author_sort |
Yi-Chuan Huang |
title |
A 6-year Retrospective Epidemiologic Study of Pediatric Pneumococcal Pneumonia in Taiwan |
title_short |
A 6-year Retrospective Epidemiologic Study of Pediatric Pneumococcal Pneumonia in Taiwan |
title_full |
A 6-year Retrospective Epidemiologic Study of Pediatric Pneumococcal Pneumonia in Taiwan |
title_fullStr |
A 6-year Retrospective Epidemiologic Study of Pediatric Pneumococcal Pneumonia in Taiwan |
title_full_unstemmed |
A 6-year Retrospective Epidemiologic Study of Pediatric Pneumococcal Pneumonia in Taiwan |
title_sort |
6-year retrospective epidemiologic study of pediatric pneumococcal pneumonia in taiwan |
publisher |
Elsevier |
series |
Journal of the Formosan Medical Association |
issn |
0929-6646 |
publishDate |
2008-12-01 |
description |
Community-acquired pneumonia (CAP) is one of the most common diseases during childhood, and its features vary between countries. Death from CAP is rare in industrialized countries, but it is the leading cause of mortality in developing countries. The purpose of this study was to determine the epidemiology and morbidity of pneumococcal CAP (PCAP) in children hospitalized with pneumonia in Taiwan.
Methods: We retrospectively screened the medical records of 12,914 children hospitalized with pneumonia at four hospitals in Taiwan from 2000 to 2005. This included a suspected PCAP group (2350 patients) and a group with likely/definite pneumococcal pneumonia (PP group, 901 patients).
Results: From 2000, the frequency of suspected PCAP increased gradually every year, and peaked in 2003 (22.14%); while the proportion of likely/definite PP was highest in 2004 (9.75%). The likely/definite PP group accounted for 6.98% of the hospitalized pneumonia patients from 2000 to 2005. Of children hospitalized with pneumonia, 17.9% of the suspected PCAP group and 21.3% of the PP group were admitted to the intensive care unit (ICU). Twenty-three patients died (14 in the PCAP and 9 in the PP groups) and nine (5 in the PCAP and 4 in the PP groups) were discharged with sequelae.
Conclusion: Our results indicate that children hospitalized with PCAP are common in Taiwan. About 20% of these children need ICU admissions, and some still have a poor outcome. Effective immunization programs with pneumococcal conjugate vaccine are needed for disease control and prevention. |
topic |
bacterial community acquired pneumonia epidemiological study immunization Streptococcus pneumoniae |
url |
http://www.sciencedirect.com/science/article/pii/S0929664609600188 |
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