MicroRNA and mRNA expression associated with ectopic germinal centers in thymus of myasthenia gravis.

MicroRNA and mRNA expression associated with ectopic germinal centers in thymus of myasthenia gravis.

BACKGROUND:A characteristic pathology of early onset myasthenia gravis is thymic hyperplasia with ectopic germinal centers (GC). However, the mechanisms that trigger and maintain thymic hyperplasia are poorly characterized. Dysregulation of small, non-coding microRNAs (miRNAs) and their target genes...

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Bibliographic Details
Main Authors: Manjistha Sengupta, Bi-Dar Wang, Norman H Lee, Alexander Marx, Linda L Kusner, Henry J Kaminski
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2018-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC6181382?pdf=render

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