Probing Membrane Protein Interactions by 19F Solid-State NMR

The 19F nucleus has a high gyromagnetic ratio that is comparable to that of proton. Due to its high sensitivity and low background in the biological systems, 19F labeling has emerged as an attractive approach in biological solid-state NMR studies. In this review, we summarized the widely used 19F-la...

Full description

Bibliographic Details
Main Authors:	XU Xiao-jun, WANG Shen-lin
Format:	Article
Language:	zho
Published:	Science Press 2019-06-01
Series:	Chinese Journal of Magnetic Resonance
Subjects:	19F solid-state NMR protein interaction review membrane protein
Online Access:	http://html.rhhz.net/bpxzz/html/20190212.htm

id	doaj-f8285ed4452f4d91b54c1ec165256ce3
record_format	Article
spelling	doaj-f8285ed4452f4d91b54c1ec165256ce32020-11-25T02:04:18ZzhoScience PressChinese Journal of Magnetic Resonance1000-45561000-45562019-06-01362238251Probing Membrane Protein Interactions by 19F Solid-State NMRXU Xiao-jun0 WANG Shen-lin11. College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China; 2. Beijing NMR Center, Peking University, Beijing 100871, China1. College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China; 2. Beijing NMR Center, Peking University, Beijing 100871, China; 3. National Laboratories of Beijing National Laboratory for Molecular Science, Beijing 100871, ChinaThe 19F nucleus has a high gyromagnetic ratio that is comparable to that of proton. Due to its high sensitivity and low background in the biological systems, 19F labeling has emerged as an attractive approach in biological solid-state NMR studies. In this review, we summarized the widely used 19F-labeling strategies, 19F solid-state NMR spectroscopy techniques to probe membrane protein interactions, and the recent applications of 19F solid-state NMR in characterizing of membrane proteins. The limitations of 19F solid-state NMR were also highlighted.http://html.rhhz.net/bpxzz/html/20190212.htm19F solid-state NMRprotein interactionreviewmembrane protein
collection	DOAJ
language	zho
format	Article
sources	DOAJ
author	XU Xiao-jun WANG Shen-lin
spellingShingle	XU Xiao-jun WANG Shen-lin Probing Membrane Protein Interactions by 19F Solid-State NMR Chinese Journal of Magnetic Resonance 19F solid-state NMR protein interaction review membrane protein
author_facet	XU Xiao-jun WANG Shen-lin
author_sort	XU Xiao-jun
title	Probing Membrane Protein Interactions by 19F Solid-State NMR
title_short	Probing Membrane Protein Interactions by 19F Solid-State NMR
title_full	Probing Membrane Protein Interactions by 19F Solid-State NMR
title_fullStr	Probing Membrane Protein Interactions by 19F Solid-State NMR
title_full_unstemmed	Probing Membrane Protein Interactions by 19F Solid-State NMR
title_sort	probing membrane protein interactions by 19f solid-state nmr
publisher	Science Press
series	Chinese Journal of Magnetic Resonance
issn	1000-4556 1000-4556
publishDate	2019-06-01
description	The 19F nucleus has a high gyromagnetic ratio that is comparable to that of proton. Due to its high sensitivity and low background in the biological systems, 19F labeling has emerged as an attractive approach in biological solid-state NMR studies. In this review, we summarized the widely used 19F-labeling strategies, 19F solid-state NMR spectroscopy techniques to probe membrane protein interactions, and the recent applications of 19F solid-state NMR in characterizing of membrane proteins. The limitations of 19F solid-state NMR were also highlighted.
topic	19F solid-state NMR protein interaction review membrane protein
url	http://html.rhhz.net/bpxzz/html/20190212.htm
work_keys_str_mv	AT xuxiaojun probingmembraneproteininteractionsby19fsolidstatenmr AT wangshenlin probingmembraneproteininteractionsby19fsolidstatenmr
_version_	1724943275216863232

Probing Membrane Protein Interactions by 19F Solid-State NMR

Similar Items