A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders

A polyepigenetic glucocorticoid exposure score at birth and childhood mental and behavioral disorders

Background: Maternal depression and anxiety during pregnancy may enhance fetal exposure to glucocorticoids (GCs) and harm neurodevelopment. We tested whether a novel cross-tissue polyepigenetic biomarker indicative of in utero exposure to GC is associated with mental and behavioral disorders and the...

Full description

Bibliographic Details
Main Authors:	Anna Suarez, Jari Lahti, Marius Lahti-Pulkkinen, Polina Girchenko, Darina Czamara, Janine Arloth, Anni LK. Malmberg, Esa Hämäläinen, Eero Kajantie, Hannele Laivuori, Pia M. Villa, Rebecca M. Reynolds, Nadine Provençal, Elisabeth B. Binder, Katri Räikkönen
Format:	Article
Language:	English
Published:	Elsevier 2020-11-01
Series:	Neurobiology of Stress
Subjects:	Cord blood methylation Glucocorticoids Polyepigenetic biomarker Childhood mental health Prenatal psychopathology Prospective study
Online Access:	http://www.sciencedirect.com/science/article/pii/S2352289520300655

Similar Items

The epigenetic clock and pubertal, neuroendocrine, psychiatric, and cognitive outcomes in adolescents
by: Anna Suarez, et al.
Published: (2018-07-01)

Associations between maternal risk factors of adverse pregnancy and birth outcomes and the offspring epigenetic clock of gestational age at birth
by: Polina Girchenko, et al.
Published: (2017-05-01)

Maternal Prenatal Positive Affect, Depressive and Anxiety Symptoms and Birth Outcomes: The PREDO Study.
by: Anu-Katriina Pesonen, et al.
Published: (2016-01-01)

Plasma Heme Scavengers Alpha-1-Microglobulin and Hemopexin as Biomarkers in High-Risk Pregnancies
by: Grigorios Kalapotharakos, et al.
Published: (2019-04-01)

Maternal depressive symptoms during and after pregnancy are associated with attention-deficit/hyperactivity disorder symptoms in their 3- to 6-year-old children.
by: Elina Wolford, et al.
Published: (2017-01-01)

Maternal MTHFR rs1801131 polymorphism modifies the association between maternal prenatal folate levels and developmental delay in the offspring
by: E. Särkilahti, et al.
Published: (2020-01-01)

Longitudinal changes in plasma hemopexin and alpha-1-microglobulin concentrations in women with and without clinical risk factors for pre-eclampsia.
by: Katja Murtoniemi, et al.
Published: (2019-01-01)

Maternal body mass index in pregnancy and mental disorders in adult offspring: a record linkage study in Aberdeen, Scotland
by: Marius Lahti-Pulkkinen, et al.
Published: (2021-07-01)

The pediatric buccal epigenetic clock identifies significant ageing acceleration in children with internalizing disorder and maltreatment exposure
by: Felix Dammering, et al.
Published: (2021-11-01)

Physical activity, body composition and metabolic syndrome in young adults.
by: Minna K Salonen, et al.
Published: (2015-01-01)

Personality and dietary intake - findings in the Helsinki birth cohort study.
by: Anna-Maija K Tiainen, et al.
Published: (2013-01-01)

Maternal Grand Multiparity and the Risk of Severe Mental Disorders in Adult Offspring.
by: Marius Lahti, et al.
Published: (2014-01-01)

Cluster analysis to estimate the risk of preeclampsia in the high-risk Prediction and Prevention of Preeclampsia and Intrauterine Growth Restriction (PREDO) study.
by: Pia M Villa, et al.
Published: (2017-01-01)

Prediction of pre-eclampsia and its subtypes in high-risk cohort: hyperglycosylated human chorionic gonadotropin in multivariate models
by: Katja Murtoniemi, et al.
Published: (2018-07-01)

Prenatal and childhood growth, and hospitalization for alcohol use disorders in adulthood: the Helsinki birth cohort study.
by: Jari Lahti, et al.
Published: (2014-01-01)

Psychopathology—a Precision Tool in Need of Re-sharpening
by: Frauke Schultze-Lutter, et al.
Published: (2018-09-01)

Attitudes of Medical laboratory employees towards their work environment.
by: Kolosa, Irene, Nokulunga
Published: (2013)

Mortality of young offenders: a national register-based follow-up study of 15- to 19-year-old Finnish delinquents referred for forensic psychiatric examination between 1980 and 2010
by: Nina Lindberg, et al.
Published: (2017-08-01)

Maternal and paternal psychopathological risk in children with non-organic failure to thrive
by: Luca Cerniglia, et al.
Published: (2019-12-01)

A study of sleep quality and its correlates in end-stage renal disease patients on haemodialysis
by: Shiva Kumar BK, et al.
Published: (2019-01-01)

SIRT6 polymorphism rs117385980 is associated with longevity and healthy aging in Finnish men
by: Katariina Hirvonen, et al.
Published: (2017-04-01)

The association between the quality of family relationships and child psychopathology
by: Kimhan, Cassian BK
Published: (2009)

Mothers and fathers do not accurately report each other’s psychopathology
by: Sharon K. Hunter, et al.
Published: (2012-07-01)

Talking past each other: Conceptual confusion in ‘culture’ and ‘psychopathology’
by: Mohammed Abouelleil Rashed
Published: (2013-03-01)

The methods of madness : recognizing delusional talk
by: Palmer, Derrol
Published: (1997)

Play and playfulness in psychoanalysis
by: Huber, Franziska
Published: (2002)

Neuropsychological correlates of youth psychopathy
by: Bezeau, Scott Cameron.
Published: (2008)

Psychopathology following torture experiences: a retrospective record review of victims of torture presenting to the Southern African Centre for Survivors of Torture (SACST)
by: Raghubir, Latisha
Published: (2015)

Psychopathology in patients with schizophrenia attending a psychiatry outpatient clinic at a tertiary care hospital
by: Hiranya Wijesundara, et al.
Published: (2011-06-01)

Empirical Validation of the Ontogenic Process Model of Externalizing Psychopathology in a Longitudinal Sample of Children and Adolescents
by: Bell, Ziv E.
Published: (2020)

Infant Growth after Preterm Birth and Mental Health in Young Adulthood.
by: Sara Sammallahti, et al.
Published: (2015-01-01)

Nutrition after preterm birth and adult neurocognitive outcomes.
by: Sara Sammallahti, et al.
Published: (2017-01-01)

Normal Gestational Weight Gain Protects From Large-for-Gestational-Age Birth Among Women With Obesity and Gestational Diabetes
by: Sanna Mustaniemi, et al.
Published: (2021-05-01)

Editorial: New Perspectives in Psychopathology
by: Diogo Telles Correia, et al.
Published: (2020-02-01)

An Attachment Theoretical Framework for Understanding Personality Disorders: Developmental, Neuroscience, and Psychotherapeutic Considerations
by: Kenneth N. Levy, et al.
Published: (2015-04-01)

An Attachment Theoretical Framework for Understanding Personality Disorders: Developmental, Neuroscience, and Psychotherapeutic Considerations
by: Kenneth N. Levy, et al.
Published: (2015-04-01)

Maternal prenatal anxiety and child COMT genotype predict working memory and symptoms of ADHD.
by: Kieran J O'Donnell, et al.
Published: (2017-01-01)

Phenomenology of depression: Contributions of Minkowski, Binswanger, Tellenbach and Tatossian
by: Lucas BLOC, et al.

Psychopathology of Aboriginal and Non-Aboriginal Adolescents Living in the Mountainous Region of Southern Taiwan
by: Cheng-Fang Yen, et al.
Published: (2006-11-01)

Mood, motor, and speech abnormalities in schizophrenia, mania, and other psychotic disorders: a comparative analysis
by: Dhrubajyoti Bhuyan, et al.
Published: (2019-01-01)