Gabapentin prevents oxaliplatin-induced central sensitization in the dorsal horn neurons in rats

Objective(s): The present study aims to study the alteration of glutamatergic transmission in the dorsal horn neurons and the effect of gabapentin on oxaliplatin-induced neuropathic pain in rats. Materials and Methods: Oxaliplatin (5 mg/kg) or saline was administered to adult male Sprague-Dawley rat...

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Bibliographic Details
Main Authors: Teng Ruyang, Zhao Yang, Feng Wei
Format: Article
Language:English
Published: Mashhad University of Medical Sciences 2015-05-01
Series:Iranian Journal of Basic Medical Sciences
Subjects:
Online Access:http://ijbms.mums.ac.ir/pdf_4413_722e70346296289a75418dd23ea95d66.html