Iron and Oxidative Stress in Parkinson's Disease: An Observational Study of Injury Biomarkers.

Iron and Oxidative Stress in Parkinson's Disease: An Observational Study of Injury Biomarkers.

Parkinson's disease (PD) is characterized by progressive motor impairment attributed to progressive loss of dopaminergic neurons in the substantia nigra (SN) pars compacta. In addition to an accumulation of iron, there is also an increased production of reactive oxygen/nitrogen species (ROS/RNS...

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Main Authors: Marcio S Medeiros, Arthur Schumacher-Schuh, Andreia Machado Cardoso, Guilherme Vargas Bochi, Jucimara Baldissarelli, Aline Kegler, Daniel Santana, Carolina Maria Martins Behle Soares Chaves, Maria Rosa Chitolina Schetinger, Rafael Noal Moresco, Carlos R M Rieder, Michele Rechia Fighera
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2016-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC4709097?pdf=render

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