A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors

A scalable solution for isolating human multipotent clinical-grade neural stem cells from ES precursors

Abstract Background A well-characterized method has not yet been established to reproducibly, efficiently, and safely isolate large numbers of clinical-grade multipotent human neural stem cells (hNSCs) from embryonic stem cells (hESCs). Consequently, the transplantation of neurogenic/gliogenic precu...

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Bibliographic Details
Main Authors: Dasa Bohaciakova, Marian Hruska-Plochan, Rachel Tsunemoto, Wesley D. Gifford, Shawn P. Driscoll, Thomas D. Glenn, Stephanie Wu, Silvia Marsala, Michael Navarro, Takahiro Tadokoro, Stefan Juhas, Jana Juhasova, Oleksandr Platoshyn, David Piper, Vickie Sheckler, Dara Ditsworth, Samuel L. Pfaff, Martin Marsala
Format: Article
Language:English
Published: BMC 2019-03-01
Series:Stem Cell Research & Therapy
Subjects:
Human embryonic stem cell (hESC)
Neural stem cell (NSC)
Spinal cord
Amyotrophic lateral sclerosis (ALS)
Spinal traumatic injury
Bioinformatic tools to study xenografts
Online Access:http://link.springer.com/article/10.1186/s13287-019-1163-7

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http://link.springer.com/article/10.1186/s13287-019-1163-7

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