Leucine-rich glioma inactivated-1 and voltage gated potassium channel autoimmune encephalitis associated with ischemic stroke; A Case Report

• Main Authors: Marisa Patryce McGinley, Sarkis eMorales Vidal, Sean eRuland
• Format: Article
• Language: English
• Published: Frontiers Media S.A. 2016-05-01
• Series: Frontiers in Neurology
• Subjects: Limbic Encephalitis; ischemic stroke; autoimmune encephalitis; Voltage gated potassium channel; Leucine-rich glioma inactivated-1
• Online Access: http://journal.frontiersin.org/Journal/10.3389/fneur.2016.00068/full

Autoimmune encephalitis is associated with a wide variety of antibodies and clinical presentations. Voltage gated potassium channel (VGKC) antibodies are a cause of autoimmune non-paraneoplastic encephalitis characterized by memory impairment, psychiatric symptoms, and seizures. We present a case of VGKC encephalitis likely preceding an ischemic stroke. Reports of autoimmune encephalitis associated with ischemic stroke are rare. Several hypothesizes linking these two disease processes are proposed.