Interaction of rocuronium with human liver cytochromes P450

Interaction of rocuronium with human liver cytochromes P450

Rocuronium is a neuromuscular blocking agent acting as a competitive antagonist of acetylcholine. Results of an inhibition of eight individual liver microsomal cytochromes P450 (CYP) are presented. As the patients are routinely premedicated with diazepam, possible interaction of diazepam with rocuro...

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Bibliographic Details
Main Authors: Eva Anzenbacherova, Alena Spicakova, Lenka Jourova, Jitka Ulrichova, Milan Adamus, Petr Bachleda, Pavel Anzenbacher
Format: Article
Language:English
Published: Elsevier 2015-02-01
Series:Journal of Pharmacological Sciences
Subjects:
Rocuronium
Cytochrome P450
Drug interactions
Online Access:http://www.sciencedirect.com/science/article/pii/S1347861314000279

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