Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 Years

Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 Years

The patient was contaminated with multiple radionuclides 38 years ago due to an accident. To investigate the effects of radionuclide contamination on humans, he has been followed up by examinations for many years. Long-term effects gradually emerge in these years. Lung cancer was diagnosed by medica...

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Main Authors: Huahui Bian, Youyou Wang, Weibo Chen, Yusong Zhang, Zhixiang Zhuang, Rui Xia, Hong Dai, Junchao Feng, Wangyang Pu, Lei Chen, Wu Cai, Wentao Hu, Yulong Liu
Format: Article
Language:English
Published: SAGE Publishing 2018-12-01
Series:Dose-Response
Online Access:https://doi.org/10.1177/1559325818815019
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spelling doaj-f8c694cf4f9a409d9f64136ed2cbdeb32020-11-25T02:34:07ZengSAGE PublishingDose-Response1559-32582018-12-011610.1177/1559325818815019Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 YearsHuahui Bian0Youyou Wang1Weibo Chen2Yusong Zhang3Zhixiang Zhuang4Rui Xia5Hong Dai6Junchao Feng7Wangyang Pu8Lei Chen9Wu Cai10Wentao Hu11Yulong Liu12 Department of Nuclear Accident Medical Emergency, The Second Affiliated Hospital of Soochow University, Suzhou, China Department of Nuclear Accident Medical Emergency, The Second Affiliated Hospital of Soochow University, Suzhou, China Department of Nuclear Accident Medical Emergency, The Second Affiliated Hospital of Soochow University, Suzhou, China Department of Nuclear Accident Medical Emergency, The Second Affiliated Hospital of Soochow University, Suzhou, China Department of Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, China Department of Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, China Department of Nuclear Accident Medical Emergency, The Second Affiliated Hospital of Soochow University, Suzhou, China Department of Nuclear Accident Medical Emergency, The Second Affiliated Hospital of Soochow University, Suzhou, China Department of Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, China Department of Oncology, the Second Affiliated Hospital of Soochow University, Suzhou, China Department of Medical Imaging, the Second Affiliated Hospital of Soochow University, Suzhou,China Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Suzhou, China Collaborative Innovation Center of Radiological Medicine of Jiangsu Higher Education Institutions, Suzhou, ChinaThe patient was contaminated with multiple radionuclides 38 years ago due to an accident. To investigate the effects of radionuclide contamination on humans, he has been followed up by examinations for many years. Long-term effects gradually emerge in these years. Lung cancer was diagnosed by medical examinations. Besides, chronic gastritis with intestinal metaplasia was indicated by gastroscopic biopsies, while colorectal polyps found by colonoscopy. All 13 colorectal polyps were removed, and radical surgery for lung cancer was performed. Fortunately, pathological examinations indicated that it was early lung cancer. The ground glass nodule (GGN) in left lung identified during the follow-up will be resected when needed. It is speculated that multiple manifestations of the patient may be related to radiation, and different lesions in the organs may be related to systemic adaptive response. However, longer follow-up is needed due to a lack of effective and direct evidence. This work is expected to provide experiences for similar patients’ treatment and follow-up.https://doi.org/10.1177/1559325818815019
collection DOAJ
language English
format Article
sources DOAJ
author Huahui Bian
Youyou Wang
Weibo Chen
Yusong Zhang
Zhixiang Zhuang
Rui Xia
Hong Dai
Junchao Feng
Wangyang Pu
Lei Chen
Wu Cai
Wentao Hu
Yulong Liu
spellingShingle Huahui Bian
Youyou Wang
Weibo Chen
Yusong Zhang
Zhixiang Zhuang
Rui Xia
Hong Dai
Junchao Feng
Wangyang Pu
Lei Chen
Wu Cai
Wentao Hu
Yulong Liu
Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 Years
Dose-Response
author_facet Huahui Bian
Youyou Wang
Weibo Chen
Yusong Zhang
Zhixiang Zhuang
Rui Xia
Hong Dai
Junchao Feng
Wangyang Pu
Lei Chen
Wu Cai
Wentao Hu
Yulong Liu
author_sort Huahui Bian
title Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 Years
title_short Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 Years
title_full Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 Years
title_fullStr Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 Years
title_full_unstemmed Multiple Organ Lesions in a Case of Contamination With Multiple Radionuclides After 38 Years
title_sort multiple organ lesions in a case of contamination with multiple radionuclides after 38 years
publisher SAGE Publishing
series Dose-Response
issn 1559-3258
publishDate 2018-12-01
description The patient was contaminated with multiple radionuclides 38 years ago due to an accident. To investigate the effects of radionuclide contamination on humans, he has been followed up by examinations for many years. Long-term effects gradually emerge in these years. Lung cancer was diagnosed by medical examinations. Besides, chronic gastritis with intestinal metaplasia was indicated by gastroscopic biopsies, while colorectal polyps found by colonoscopy. All 13 colorectal polyps were removed, and radical surgery for lung cancer was performed. Fortunately, pathological examinations indicated that it was early lung cancer. The ground glass nodule (GGN) in left lung identified during the follow-up will be resected when needed. It is speculated that multiple manifestations of the patient may be related to radiation, and different lesions in the organs may be related to systemic adaptive response. However, longer follow-up is needed due to a lack of effective and direct evidence. This work is expected to provide experiences for similar patients’ treatment and follow-up.
url https://doi.org/10.1177/1559325818815019
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