Host Cell S Phase Restricts Legionella pneumophila Intracellular Replication by Destabilizing the Membrane-Bound Replication Compartment

Legionella pneumophila grows within cells ranging from environmental amoebae to human macrophages. In spite of this conserved strategy of pathogenesis, identification of host factors that restrict L. pneumophila intracellular replication has not been extended outside components of the mammalian inna...

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Bibliographic Details
Main Authors: Dennise A. de Jesús-Dúíaz, Connor Murphy, Asaf Sol, Marion Dorer, Ralph R. Isberg, Samuel I. Miller
Format: Article
Language:English
Published: American Society for Microbiology 2017-08-01
Series:mBio
Online Access:http://mbio.asm.org/cgi/content/full/8/4/e02345-16